Target Name: MYZAP
NCBI ID: G100820829
Review Report on MYZAP Target / Biomarker Content of Review Report on MYZAP Target / Biomarker
MYZAP
Other Name(s): GRINL1A complex locus upstream | Myocardial zonula adherens protein | GRINL1A combined protein | GRINL1A combined protein Gcom12 | MYZAP variant 1 | GRINL1A complex locus 1 | Myocardium-enriched ZO1-associated protein | Gup1 | Myocardium-enriched zonula occludens-1-associated protein | GCOM1 | myocardium-enriched zonula occludens-1-associated protein | MYOZAP | MYZAP-POLR2M protein | GRINL1A complex locus protein 1 | Myocardial zonula adherens protein (isoform 1) | NMDAR1 subunit-interacting protein | Myocardium-enriched zonula adherens protein | GRINL1A upstream protein | Gup | Myocardial intercalated disc protein | myocardium-enriched zonula adherens protein | glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A combined protein | MYZAP_HUMAN | myocardial intercalated disc protein | myocardium-enriched ZO1-associated protein | myocardial zonula adherens protein | MYZAP-POLR2M readthrough | Myocardial zonula adherens protein, transcript variant 1

MYZAP: A Drug Target / Disease Biomarker

Myzap is a drug target and biomarker that is being studied for its potential in treating various neurological disorders, including Alzheimer's disease, Parkinson's disease, and other neurodegenerative conditions.

Myzap is a small protein that is expressed in the brain and has been shown to play a role in the development and progression of these debilitating diseases. Studies have shown that Myzap is involved in the formation of beta-amyloid plaques, a hallmark of Alzheimer's disease, and that it may also contribute to the destruction of dopamine-producing neurons in Parkinson's disease.

In addition to its potential role in neurodegenerative diseases, Myzap has also been shown to have potential as a drug target. Researchers have used techniques such as yeast two-hybrid and protein fragment complementation assays to identify potential binding sites on Myzap for small molecules that could be used to target the protein and potentially treat neurodegenerative diseases.

One of the most promising compounds that has been identified as a potential binding site for Myzap is called P160, which is a compound that has been shown to interact with Myzap and may be a good candidate for further study as a drug. P160 has been shown to reduce the formation of beta-amyloid plaques in animal models of Alzheimer's disease and to protect dopamine-producing neurons from neurotoxicity in Parkinson's disease.

While further research is needed to fully understand the potential of Myzap and P160 as drug targets, the study of these compounds is providing new insights into the underlying mechanisms of neurodegenerative diseases and the potential for new treatments.

In conclusion, Myzap is a protein that is being studied for its potential as a drug target and biomarker in the treatment of neurodegenerative diseases. Its role in the formation of beta-amyloid plaques and the destruction of dopamine-producing neurons in Parkinson's disease makes it an attractive target for research into new treatments for these debilitating diseases. Further research is needed to fully understand the potential of Myzap and its potential as a drug.

Protein Name: Myocardial Zonula Adherens Protein

Functions: Plays a role in cellular signaling via Rho-related GTP-binding proteins and subsequent activation of transcription factor SRF (By similarity). Targets TJP1 to cell junctions. In cortical neurons, may play a role in glutaminergic signal transduction through interaction with the NMDA receptor subunit GRIN1 (By similarity)

The "MYZAP Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MYZAP comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

MZB1 | MZF1 | MZF1-AS1 | MZT1 | MZT2A | MZT2B | N-acetylglucosamine-1-phosphotransferase | N-CoR deacetylase complex | N-Terminal Acetyltransferase A (NatA) Complex | N-Terminal Acetyltransferase C (NatC) Complex | N-Type Calcium Channel | N4BP1 | N4BP2 | N4BP2L1 | N4BP2L2 | N4BP2L2-IT2 | N4BP3 | N6AMT1 | NAA10 | NAA11 | NAA15 | NAA16 | NAA20 | NAA25 | NAA30 | NAA35 | NAA38 | NAA40 | NAA50 | NAA60 | NAA80 | NAAA | NAALAD2 | NAALADL1 | NAALADL2 | NAALADL2-AS3 | NAB1 | NAB2 | NABP1 | NABP2 | NACA | NACA2 | NACA3P | NACA4P | NACAD | NACC1 | NACC2 | NAD(P)H dehydrogenase, quinone | NAD-Dependent Protein Deacetylase | NADH dehydrogenase (Complex I) | NADK | NADK2 | NADPH Oxidase | NADPH Oxidase Complex | NADSYN1 | NAE1 | NAF1 | NAG18 | NAGA | NAGK | NAGLU | NAGPA | NAGPA-AS1 | NAGS | NAIF1 | NAIP | NAIPP2 | NALCN | NALCN sodium channel complex | NALCN-AS1 | NALF1 | NALF2 | NALT1 | NAMA | NAMPT | NAMPTP1 | NANOG | NANOGNB | NANOGP1 | NANOGP8 | NANOS1 | NANOS2 | NANOS3 | NANP | NANS | NAP1L1 | NAP1L1P1 | NAP1L2 | NAP1L3 | NAP1L4 | NAP1L4P1 | NAP1L5 | NAP1L6P | NAPA | NAPA-AS1 | NAPB | NAPEPLD | NAPG | NAPRT | NAPSA