NAA25: A Potential Drug Target and Biomarker for Inflammatory Diseases

Target Name: NAA25

NCBI ID: G80018

NAA25

NAA25: A Potential Drug Target and Biomarker for Inflammatory Diseases

Abstract:

NAA25, a novel adapter protein, has been identified as a potential drug target and biomarker for inflammatory diseases. Its unique structure and function make NAA25 an attractive target for small molecule inhibitors. This review summarizes the current understanding of NAA25 and its potential in the treatment of inflammatory diseases, including its potential as a drug target and biomarker.

Introduction:

Inflammatory diseases, such as rheumatoid arthritis, inflammatory bowel disease, and neuroinflammatory disorders, affect millions of people worldwide and cause significant morbidity and mortality. Chronic inflammation in these diseases can lead to chronic pain, decreased quality of life, and even early death. Therefore , the development of new treatments for these diseases is crucial.

NAA25, a novel adapter protein, has been identified as a potential drug target and biomarker for inflammatory diseases. Its unique structure and function make NAA25 an attractive target for small molecule inhibitors. This review summarizes the current understanding of NAA25 and its potential in the treatment of inflammatory diseases, including its potential as a drug target and biomarker.

Structure and Function of NAA25:

NAA25 is a 21-kDa adapter protein that contains a unique N-terminal region, a central region, and a C-terminal region. The N-terminal region contains a nucleotide acid that can interact with the adapter protein's C-terminus. The central region is responsible for the protein's stability and functions as a scaffold. The C-terminal region contains a unique glycophosphorylation site that can interact with small molecules, such as drugs, making NAA25 a potential drug target.

NAA25's Unique Structure and Function:

NAA25's unique structure and function make it an attractive target for small molecule inhibitors. Its N-terminal region is conserved and has been implicated in various cellular processes, including cell adhesion, migration, and invasion. Therefore, inhibitors that interact with NAA25's N-terminus may have broad effects on cellular processes and may be useful for treating inflammatory diseases.

In addition, NAA25's central region is responsible for its stability and functions as a scaffold. The central region has been shown to be involved in various cellular processes, including the regulation of cell adhesion, migration, and invasion. Therefore, inhibitors that interact with NAA25's The central region may have specific effects on these processes and may be useful for treating inflammatory diseases.

Furthermore, NAA25's C-terminal region is responsible for its unique glycophosphorylation site. This site can interact with small molecules, such as drugs, making NAA25 a potential drug target. Therefore, inhibitors that interact with NAA25's C-terminus may have specific effects on cellular processes and may be useful for treating inflammatory diseases.

Potential Applications of NAA25 as a Drug Target:

NAA25's unique structure and function make it an attractive target for small molecule inhibitors. Its N-terminal region is conserved and has been implicated in various cellular processes, making inhibitors that interact with NAA25's N-terminus potentially effective for treating inflammatory diseases.

In addition, NAA25's central region is responsible for its stability and functions as a scaffold, making it a potential target for inhibitors that affect cellular processes involved in inflammation.

Furthermore, NAA25's C-terminal region is unique due to its glycophosphorylation site, making it a potential target for small molecules that inhibit cellular processes involved in inflammation.

Potential Applications of NAA25 as a Biomarker:

NAA25 can also be used as a biomarker for

Protein Name: N-alpha-acetyltransferase 25, NatB Auxiliary Subunit

Functions: Non-catalytic subunit of the NatB complex which catalyzes acetylation of the N-terminal methionine residues of peptides beginning with Met-Asp, Met-Glu, Met-Asn and Met-Gln. May play a role in normal cell-cycle progression

The "NAA25 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NAA25 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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