Target Name: MYOZ3
NCBI ID: G91977
Review Report on MYOZ3 Target / Biomarker Content of Review Report on MYOZ3 Target / Biomarker
MYOZ3
Other Name(s): calsarcin-3 | Calsarcin-3 | CS-3 | Myozenin 3, transcript variant 1 | Myozenin-3 | myozenin-3 | CS3 | FATZ-related protein 3 | MYOZ3_HUMAN | myozenin 3 | FRP3 | MYOZ3 variant 1 | FATZ-3

Myoz3: Potential Drug Target and Biomarker for Diseases

Myoz3 (also known as calsarcin-3) is a protein that is expressed in various tissues throughout the body, including the lungs, heart, kidneys, and intestines. It is a member of the calbindin family of proteins, which are involved in cell signaling and tissue organization. One of the unique features of Myoz3 is its ability to interact with other proteins, including the transcription factor nuclear factor E2F1, which is known for its role in regulating gene expression.

Despite its importance in various physiological processes, Myoz3 is not well understood, and there are limited research studies available on its role in disease. However, recent studies have suggested that Myoz3 may be a drug target or biomarker, with potential applications in the treatment of various diseases. In this article, we will explore the potential of Myoz3 as a drug target and its potential as a biomarker for disease diagnosis and progression.

Myoz3 as a Drug Target

The potential of Myoz3 as a drug target is based on its unique structure and the interactions it has with other proteins, including nuclear factor E2F1. Nuclear factor E2F1 is a transcription factor that plays a critical role in regulating gene expression by binding to specific DNA sequences. It has been shown to be involved in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the key features of Myoz3 is its ability to interact with nuclear factor E2F1. This interaction may allow Myoz3 to modulate the activity of E2F1, leading to changes in gene expression that are beneficial or harmful to the cell. This is an attractive idea for drug development, as it may be possible to target Myoz3 to modulate the activity of E2F1 and improve the efficacy of certain therapies.

In addition, Myoz3 has been shown to be involved in the regulation of cellular processes that are important for cancer progression. For example, studies have shown that Myoz3 is involved in the regulation of cell adhesion, which is a critical process for the development of cancer cells. Additionally, Myoz3 has been shown to play a role in the regulation of cell apoptosis, which is a natural process that helps remove damaged or dysfunctional cells from the body.

Myoz3 as a Biomarker

The potential of Myoz3 as a biomarker for disease diagnosis and progression is based on its expression in various tissues and its ability to interact with other proteins. One of the key applications of Myoz3 as a biomarker is its potential to be used as a diagnostic marker for diseases, such as cancer.

Studies have shown that Myoz3 is often expressed in various tissues and has been associated with the development of various diseases, including cancer. For example, studies have shown that Myoz3 is often expressed in the lungs of smokers and that it is associated with an increased risk of lung cancer. Additionally, Myoz3 has been shown to be involved in the regulation of cellular processes that are important for cancer progression, which may be used as a biomarker for the detection and prognosis of cancer.

Another application of Myoz3 as a biomarker is its potential to be used as a therapeutic target. By modulating the activity of nuclear factor E2F1, Myoz3 may be able to improve the efficacy of certain therapies and reduce the risk of relapse. Additionally, by targeting Myoz3 as a biomarker, researchers may be able to identify new therapeutic approaches for diseases that are currently untreated or under-treated.

Conclusion

In conclusion, Myoz3 is a protein that is expressed in various tissues throughout the body and has been associated with the development of various diseases. Its unique structure and ability to interact with other proteins, including nuclear factor E2F1, make it an attractive candidate for drug development. Additionally, its expression in various tissues and its ability to act as a biomarker for disease diagnosis and progression make it a promising tool for the development of new therapeutic approaches for a variety of diseases. Further research is needed to fully understand the role of Myoz3 in disease and to develop safe and effective therapies that target it.

Protein Name: Myozenin 3

Functions: Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis

The "MYOZ3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MYOZ3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

MYPN | MYPOP | MYRF | MYRF-AS1 | MYRFL | MYRIP | MYSM1 | MYT1 | MYT1L | MYT1L-AS1 | MYZAP | MZB1 | MZF1 | MZF1-AS1 | MZT1 | MZT2A | MZT2B | N-acetylglucosamine-1-phosphotransferase | N-CoR deacetylase complex | N-Terminal Acetyltransferase A (NatA) Complex | N-Terminal Acetyltransferase C (NatC) Complex | N-Type Calcium Channel | N4BP1 | N4BP2 | N4BP2L1 | N4BP2L2 | N4BP2L2-IT2 | N4BP3 | N6AMT1 | NAA10 | NAA11 | NAA15 | NAA16 | NAA20 | NAA25 | NAA30 | NAA35 | NAA38 | NAA40 | NAA50 | NAA60 | NAA80 | NAAA | NAALAD2 | NAALADL1 | NAALADL2 | NAALADL2-AS3 | NAB1 | NAB2 | NABP1 | NABP2 | NACA | NACA2 | NACA3P | NACA4P | NACAD | NACC1 | NACC2 | NAD(P)H dehydrogenase, quinone | NAD-Dependent Protein Deacetylase | NADH dehydrogenase (Complex I) | NADK | NADK2 | NADPH Oxidase | NADPH Oxidase Complex | NADSYN1 | NAE1 | NAF1 | NAG18 | NAGA | NAGK | NAGLU | NAGPA | NAGPA-AS1 | NAGS | NAIF1 | NAIP | NAIPP2 | NALCN | NALCN sodium channel complex | NALCN-AS1 | NALF1 | NALF2 | NALT1 | NAMA | NAMPT | NAMPTP1 | NANOG | NANOGNB | NANOGP1 | NANOGP8 | NANOS1 | NANOS2 | NANOS3 | NANP | NANS | NAP1L1 | NAP1L1P1 | NAP1L2 | NAP1L3