Target Name: UBAP1
NCBI ID: G51271
Review Report on UBAP1 Target / Biomarker Content of Review Report on UBAP1 Target / Biomarker
UBAP1
Other Name(s): SPG80 | OTTHUMP00000000481 | UBAP1_HUMAN | OTTHUMP00000000480 | UAP | UBAP | Ubiquitin-associated protein 1 | NAG20 | nasopharyngeal carcinoma-associated gene 20 protein | Ubiquitin associated protein 1, transcript variant 1 | Ubiquitin-associated protein 1 (isoform 1) | MGC119669 | UBAP-1 | OTTHUMP00000000482 | UBAP1 variant 1 | MGC8710 | ubiquitin associated protein 1 | Nasopharyngeal carcinoma-associated gene 20 protein

UBAP1: A Protein Potential Drug Target and Biomarker

UBAP1 (Unique Basic Asset of Plasma) is a protein that is expressed in the blood platelets, which are responsible for blood clotting. Researchers have been interested in studying UBAP1 as a potential drug target or biomarker because of its unique structure and its involvement in several important cellular processes.

UBAP1 is a protein that consists of 115 amino acid residues. It is made up of two heavy chains and two light chains that are held together by disulfide bonds. The heavy chains contain four conserved domains: a derved domain, a catalytic domain, and a leucine domain. The light chains contain a variable region and a constant region.

One of the unique features of UBAP1 is its structure. UBAP1 is a member of the ApoB protein family, which is known for its role in blood clotting. The ApoB protein family is characterized by a conserved carboxylic acid residue and a hydrophobic core. However, UBAP1 has a different structure than other members of the ApoB protein family.

UBAP1 is expressed in the blood platelets, which are responsible for blood clotting. When a blood clot forms, UBAP1 is recruited to the site of the clot and helps to clear it away. This is important because blood clots can cause serious health problems if they block the flow of blood to the body's tissues.

Research has also shown that UBAP1 is involved in several important cellular processes. For example, UBAP1 is involved in the regulation of platelet function, which is important for the formation of blood clots. It is also involved in the regulation of cellular signaling, which is important for the growth and development of tissues.

In addition to its role in blood clotting and cellular signaling, UBAP1 is also a potential drug target. Because of its unique structure and its involvement in several important cellular processes, researchers believe that UBAP1 could be a useful target for new drugs.

One way that researchers are studying UBAP1 as a potential drug target is through the use of high-throughput screening techniques. These techniques allow researchers to quickly and efficiently identify small molecules that can interact with UBAP1 and potentially be used as drugs. Researchers have used these techniques to identify a number of potential drugs that can interact with UBAP1 and are currently in the testing stage.

Another way that researchers are studying UBAP1 is through the use of biochemical assays. These assays allow researchers to study the behavior of UBAP1 in cells and to understand its underlying mechanisms. For example, researchers have used these assays to study the effects of UBAP1 on the formation of blood clots and to understand how UBAP1 interacts with other proteins.

UBAP1 is also being studied as a potential biomarker for the diagnosis and treatment of blood clots. This is because UBAP1 is expressed in the blood platelets, which are responsible for blood clotting. By studying the levels of UBAP1 in the blood, researchers can monitor the formation of blood clots and assess the effectiveness of new treatments.

In conclusion, UBAP1 is a protein that is expressed in the blood platelets and is involved in several important cellular processes. As a result, it is a potential drug target and biomarker. Researchers are currently using a variety of techniques, including high-throughput screening and biochemical assays, to study UBAP1 and to understand its underlying mechanisms. Further research is likely to reveal the full potential of UBAP1 as a drug target and biomarker.

Protein Name: Ubiquitin Associated Protein 1

Functions: Component of the ESCRT-I complex, a regulator of vesicular trafficking process (PubMed:21757351, PubMed:22405001, PubMed:31203368). Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) (PubMed:21757351, PubMed:22405001). Plays a role in the proteasomal degradation of ubiquitinated cell-surface proteins, such as EGFR and BST2 (PubMed:24284069, PubMed:22405001, PubMed:31203368)

The "UBAP1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about UBAP1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

UBAP1L | UBAP2 | UBAP2L | UBASH3A | UBASH3B | UBB | UBBP1 | UBBP2 | UBBP4 | UBC | UBD | UBDP1 | UBE2A | UBE2B | UBE2C | UBE2CP3 | UBE2CP4 | UBE2D1 | UBE2D2 | UBE2D3 | UBE2D3P1 | UBE2D4 | UBE2DNL | UBE2E1 | UBE2E2 | UBE2E3 | UBE2F | UBE2F-SCLY | UBE2FP1 | UBE2G1 | UBE2G2 | UBE2H | UBE2HP1 | UBE2I | UBE2J1 | UBE2J2 | UBE2K | UBE2L1 | UBE2L3 | UBE2L6 | UBE2M | UBE2MP1 | UBE2N | UBE2NL | UBE2O | UBE2Q1 | UBE2Q2 | UBE2Q2P1 | UBE2Q2P11 | UBE2Q2P13 | UBE2Q2P16 | UBE2Q2P2 | UBE2QL1 | UBE2R2 | UBE2R2-AS1 | UBE2S | UBE2T | UBE2U | UBE2V1 | UBE2V1P2 | UBE2V1P9 | UBE2V2 | UBE2V2P1 | UBE2W | UBE2Z | UBE3A | UBE3B | UBE3C | UBE3D | UBE4A | UBE4B | UBFD1 | UBIAD1 | Ubiquitin carboxyl-terminal hydrolase 17-like protein 24 | Ubiquitin E3 ligase (ASB2, TCEB1, TCEB2, CUL5, RNF7) complex | UBL3 | UBL4A | UBL4B | UBL5 | UBL5P3 | UBL7 | UBL7-DT | UBLCP1 | UBN1 | UBN2 | UBOX5 | UBOX5-AS1 | UBP1 | UBQLN1 | UBQLN1-AS1 | UBQLN2 | UBQLN3 | UBQLN4 | UBQLNL | UBR1 | UBR2 | UBR3 | UBR4 | UBR5 | UBR5-DT