Target Name: UBE3B
NCBI ID: G89910
Review Report on UBE3B Target / Biomarker Content of Review Report on UBE3B Target / Biomarker
UBE3B
Other Name(s): MGC78388 | UBE3B_HUMAN | KOS | HECT-type ubiquitin transferase E3B | UBE2B_v1 | BPIDS | FLJ45294 | UBE3B variant 1 | ubiquitin protein ligase E3B | Ubiquitin protein ligase E3B, transcript variant 1 | DKFZp686A1051 | MGC131858 | DKFZp586K2123 | Ubiquitin-protein ligase E3B (isoform 1) | Ubiquitin-protein ligase E3B

Understanding The Role of UBE3B in Cellular Processes

UBE3B (Usp9201) is a protein that is expressed in various tissues throughout the body, including the brain. It is a member of the Usp92 family of proteins, which are involved in various cellular processes, including cell signaling, DNA replication, and repair. UBE3B is also known as MGC78388, and it has been identified as a potential drug target or biomarker for various diseases.

The Usp92 family of proteins plays a crucial role in the regulation of cell proliferation and differentiation. Usp92A and Usp92B are involved in the DNA damage response, while Usp92C and Usp92D are involved in cell signaling. Usp92E is involved in cell adhesion, and Usp92F is involved in the regulation of cell cycle progression.

UBE3B is a 21-kDa protein that is expressed in the brain, heart, liver, and various other tissues. It is involved in various cellular processes, including cell signaling, DNA replication, and repair. UBE3B is a transcription factor that has been shown to play a role in the regulation of brain development and plasticity.

One of the most significant functions of UBE3B is its role in the regulation of the neurogenic field (NF). The NF is a region of the brain that is involved in the development and function of neural stem cells and progenitor cells. UBE3B is known to play a role in the regulation of the NF, and it has been shown to be involved in the development and maintenance of neural stem cells and progenitor cells.

UBE3B is also involved in the regulation of cell signaling, including the regulation of cell proliferation and differentiation. It has been shown to play a role in the regulation of various signaling pathways, including the TGF-β pathway, the Wnt pathway, and the Hedgehog pathway.

In addition to its role in cellular signaling, UBE3B is also involved in the regulation of DNA replication and repair. It has been shown to play a role in the regulation of DNA replication in various cell types, including cancer cells.

UBE3B is also a potential drug target or biomarker for various diseases. For example, it has been shown to be involved in the development and progression of various types of cancer, including neurobladder cancer and ovarian cancer. It has also been shown to play a role in the regulation of various diseases, including neurodegenerative diseases and autoimmune diseases.

In conclusion, UBE3B is a protein that is involved in various cellular processes in the brain, including cell signaling, DNA replication, and repair. It is a potential drug target or biomarker for various diseases, including neurobladder cancer, ovarian cancer, and neurodegenerative diseases. Further research is needed to fully understand the role of UBE3B in cellular processes and its potential as a drug target or biomarker.

Protein Name: Ubiquitin Protein Ligase E3B

Functions: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates

The "UBE3B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about UBE3B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

UBE3C | UBE3D | UBE4A | UBE4B | UBFD1 | UBIAD1 | Ubiquitin carboxyl-terminal hydrolase 17-like protein 24 | Ubiquitin E3 ligase (ASB2, TCEB1, TCEB2, CUL5, RNF7) complex | UBL3 | UBL4A | UBL4B | UBL5 | UBL5P3 | UBL7 | UBL7-DT | UBLCP1 | UBN1 | UBN2 | UBOX5 | UBOX5-AS1 | UBP1 | UBQLN1 | UBQLN1-AS1 | UBQLN2 | UBQLN3 | UBQLN4 | UBQLNL | UBR1 | UBR2 | UBR3 | UBR4 | UBR5 | UBR5-DT | UBR7 | UBTD1 | UBTD2 | UBTF | UBTFL1 | UBTFL2 | UBTFL6 | UBXN1 | UBXN10 | UBXN11 | UBXN2A | UBXN2B | UBXN4 | UBXN6 | UBXN7 | UBXN8 | UCA1 | UCHL1 | UCHL1-DT | UCHL3 | UCHL5 | UCK1 | UCK2 | UCKL1 | UCKL1-AS1 | UCMA | UCN | UCN2 | UCN3 | UCP1 | UCP2 | UCP3 | UDP-Glycosyltransferase | UDP-N-Acetylglucosamine--Peptide N-Acetylglucosaminyltransferase (O-GlcNAc Transferase) | UEVLD | UFC1 | UFD1 | UFD1-AS1 | UFL1 | UFM1 | UFSP1 | UFSP2 | UGCG | UGDH | UGDH-AS1 | UGGT1 | UGGT2 | UGP2 | UGT1A1 | UGT1A10 | UGT1A3 | UGT1A4 | UGT1A5 | UGT1A6 | UGT1A7 | UGT1A8 | UGT1A9 | UGT2A1 | UGT2A2 | UGT2A3 | UGT2B10 | UGT2B11 | UGT2B15 | UGT2B17 | UGT2B27P | UGT2B28 | UGT2B29P