UBE2M: A Protein Involved in Cellular Processes and Drug Development

Target Name: UBE2M

NCBI ID: G9040

UBE2M

UBE2M: A Protein Involved in Cellular Processes and Drug Development

Ubiquitin (Ub) is a protein that plays a critical role in the regulation of protein stability and degradation. Ubiquitin is conjugated with a variety of different amino acids, including ubiquitin( ubiquitin-conjugated protein) and ubiquitin-like modifiers (UBMs) to give it its unique structure and function. Ubiquitin is widely expressed in many different cell types and is involved in a variety of cellular processes, including DNA damage repair, inflammation, and cell signaling.

The ubiquitin enzyme E2 (UBE2M) is a protein that adds a ubiquitin-like molecule, known as Ub8, to the end of target proteins. This modification has important functional consequences, as it allows Ub8 to interact with a wide range of different proteins and can influence their stability, localization, and activity. UBE2M is an enzyme that is highly conserved across different species and is found in many different cellular organelles, including the endoplasmic reticulum, the cytoplasm, and various organelles of the mitochondria.

UBE2M is a protein that is often targeted by drugs because of its role in the regulation of cellular processes and its potential as a drug target. One of the main reasons for this is that UBE2M is a conserved protein that is widely expressed in many different cells types, making it an attractive target for small molecules. Additionally, the addition of Ub8 to the end of target proteins allows UBE2M to interact with a wide range of different proteins, making it a versatile target for drug development.

UBE2M is involved in many different cellular processes, including the regulation of protein stability and degradation, DNA damage repair, and cell signaling. One of the main functions of UBE2M is to add Ub8 to the end of target proteins. This modification allows Ub8 to interact with a wide range of different proteins and can influence their stability, localization, and activity. This interaction between UBE2M and target proteins is critical for the regulation of cellular processes and is a key step in the development of new drugs.

UBE2M is also involved in the regulation of DNA damage repair. DNA damage can occur as a result of a variety of different factors, including ionizing radiation, UV radiation, and chemicals. These damages can cause proteins to become unstable and to be degraded, leading to a variety of cellular responses. UBE2M is involved in the regulation of DNA damage repair by adding Ub8 to the end of damaged proteins. This modification allows Ub8 to interact with DNA repair machinery, which can help to repair the damage and prevent the development of cancer.

UBE2M is also involved in the regulation of cell signaling. Many different signaling pathways rely on the regulation of protein stability and degradation to control cellular processes. UBE2M is involved in the regulation of these processes by adding Ub8 to the end of target proteins. This modification can influence the stability and localization of target proteins and can also affect their activity. This interaction between UBE2M and target proteins is critical for the regulation of cellular processes and is a key step in the development of new drugs.

Another function of UBE2M is to regulate the assembly and disassembly of organelles. Ubiquitin is involved in the regulation of the assembly and disassembly of various organelles, including the endoplasmic reticulum, the cytoplasm, and the mitochondria. by adding Ub8 to the end of target proteins. This modification can influence the stability and localization of target proteins and can also affect their activity. This interaction between UBE2M and target proteins is

Protein Name: Ubiquitin Conjugating Enzyme E2 M

Functions: Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX1, but not RBX2, suggests that the RBX1-UBE2M complex neddylates specific target proteins, such as CUL1, CUL2, CUL3 and CUL4. Involved in cell proliferation

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