Target Name: ICMT
NCBI ID: G23463
Review Report on ICMT Target / Biomarker Content of Review Report on ICMT Target / Biomarker
ICMT
Other Name(s): OTTHUMP00000001381 | Protein S-farnesylcysteine C-terminal methyltransferase | Protein-S isoprenylcysteine O-methyltransferase | Farnesyl-protein carboxymethyltransferase | Isoprenylcysteine carboxylmethyltransferase | prenylated protein carboxyl methyltransferase | Prenylcysteine carboxyl methyltransferase | Protein-S-isoprenylcysteine O-methyltransferase | S-farnesylcysteine methyltransferase | PCMT | HSTE14 | pcCMT | Protein C-terminal farnesylcysteine O-methyltransferase | Isoprenylcysteine carboxyl methyltransferase | PPMT | MST098 | Prenylated protein methyltransferase | MSTP098 | prenylcysteine carboxyl methyltransferase | Farnesylated protein C-terminal O-methyltransferase | MGC39955 | Isoprenylated protein methyltransferase | Prenylcysteine carboxylmethyltransferase | PcCMT | isoprenylcysteine carboxyl methyltransferase | Prenylated protein carboxyl methyltransferase | Prenylcysteine methyltransferase | Farnesyl cysteine C-terminal methyltransferase | ICMT_HUMAN | PCCMT

IMMT: A Protein Potential Drug Target

ICMT, or interleukin-12 (IL-12), is a protein that is expressed in a variety of tissues throughout the body, including the immune system, skin, and nervous system. It is a key regulator of immune cell function and has been implicated in a number of diseases, including cancer, autoimmune disorders, and obesity.

ICMT has also been identified as a potential drug target for a variety of diseases, including cancer, with studies showing that inhibiting ICMT has the potential to be an effective new treatment approach.

One of the key reasons for the potential of ICMT as a drug target is its involvement in the immune system. ICMT is a key regulator of the production and function of T cells, which are a crucial part of the immune system. T cells are responsible for recognizing and responding to foreign substances in the body, and ICMT plays a critical role in ensuring that they are able to do so effectively.

Studies have shown that ICMT is involved in the regulation of T cell development, activation, and proliferation. It has also been shown to play a role in the regulation of immune cell function and the production of antibodies, which are important components of the immune response.

In addition to its role in the immune system, ICMT has also been implicated in a number of other processes that are important for overall health and disease. For example, ICMT has been shown to play a role in the regulation of skin cell growth and differentiation , and has been implicated in the development of skin cancer. It has also been shown to be involved in the regulation of neural cell growth and differentiation, and has been implicated in the development of neurodegenerative diseases.

In addition to its involvement in the immune system and nervous system, ICMT has also been implicated in the regulation of a variety of other processes that are important for overall health and disease. For example, ICMT has been shown to play a role in the regulation of metabolism and energy homeostasis, and has been implicated in the development of diseases such as obesity and type 2 diabetes.

Overall, ICMT is a protein that has a wide range of potential applications as a drug target. Its involvement in the immune system and its role in the regulation of a variety of processes throughout the body make it an attractive target for research and development of new treatments. As more research is conducted on ICMT, it is likely to become increasingly clear just how important this protein is for human health and disease.

Protein Name: Isoprenylcysteine Carboxyl Methyltransferase

Functions: Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues

The "ICMT Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ICMT comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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ICMT-DT | ICOS | ICOSLG | ID1 | ID2 | ID2-AS1 | ID2B | ID3 | ID4 | IDE | IDH1 | IDH1-AS1 | IDH2 | IDH2-DT | IDH3A | IDH3B | IDH3G | IDI1 | IDI2 | IDI2-AS1 | IDNK | IDO1 | IDO2 | IDS | IDSP1 | IDUA | IER2 | IER3 | IER3-AS1 | IER3IP1 | IER5 | IER5L | IER5L-AS1 | IFFO1 | IFFO2 | IFI16 | IFI27 | IFI27L1 | IFI27L2 | IFI30 | IFI35 | IFI44 | IFI44L | IFI6 | IFIH1 | IFIT1 | IFIT1B | IFIT2 | IFIT3 | IFIT5 | IFITM1 | IFITM10 | IFITM2 | IFITM3 | IFITM3P2 | IFITM3P7 | IFITM4P | IFITM5 | IFITM8P | IFITM9P | IFNA1 | IFNA10 | IFNA12P | IFNA13 | IFNA14 | IFNA16 | IFNA17 | IFNA2 | IFNA21 | IFNA22P | IFNA4 | IFNA5 | IFNA6 | IFNA7 | IFNA8 | IFNAR1 | IFNAR2 | IFNB1 | IFNE | IFNG | IFNG-AS1 | IFNGR1 | IFNGR2 | IFNK | IFNL1 | IFNL2 | IFNL3 | IFNL4 | IFNLR1 | IFNW1 | IFNWP15 | IFNWP19 | IFRD1 | IFRD2 | IFT122 | IFT122P3 | IFT140 | IFT172 | IFT20 | IFT22