Target Name: KIF1A
NCBI ID: G547
Review Report on KIF1A Target / Biomarker Content of Review Report on KIF1A Target / Biomarker
KIF1A
Other Name(s): Axonal transporter of synaptic vesicles | Kinesin family member 1A | microtubule-based motor KIF1A | Unc-104- and KIF1A-related protein | HSN2C | Axonal transport of synaptic vesicles | DKFZp686I2094 | Tmp_locus_27 | unc-104- and KIF1A-related protein | Spastic paraplegia 30 (autosomal recessive) | MGC133286 | UNC104 | MRD9 | HUNC-104 | MGC133285 | KIF1A variant 2 | hUNC-104 | SPG30 | hUnc-104 | KIF1A_HUMAN | axonal transporter of synaptic vesicles | Microtubule-based motor KIF1A | Kinesin family member 1A, transcript variant 1 | Kinesin-like protein KIF1A (isoform 2) | FLJ30229 | NESCAVS | Kinesin-like protein KIF1A | Kinesin-like protein KIF1A (isoform 1) | Kinesin, heavy chain, member 1A, homolog of mouse | Kinesin family member 1A, transcript variant 2 | UNC-104- and KIF1A-related protein | C2orf20 | kinesin family member 1A | ATSV | KIF1A variant 1 | kinesin, heavy chain, member 1A, homolog of mouse

KIF1A: A Potential Drug Target and Biomarker

Kidney is one of the most crucial organs in the body that plays a vital role in maintaining the balance of vital signs, including blood pressure, temperature, and the production of hormones that regulate various bodily functions. The kidney is also responsible for removing waste products and excess fluids from the blood, which is critical for maintaining a healthy weight and regulating fluid levels throughout the body. When the kidney function is compromised, it can lead to various health problems, including diabetes, hypertension, and cardiovascular disease. As such, identifying potential drug targets and biomarkers for the kidney is of great importance for the development of new treatments for these conditions. One such potential drug target and biomarker is KIF1A, which is a gene that has been identified as a potential drug target for various diseases, including diabetes, cancer, and neurodegenerative disorders.

The KIF1A gene is located on chromosome 6 and encodes for a protein known as KIF1A, which is a key regulator of the fission yeast. KIF1A plays a critical role in the development and maintenance of the fission yeast, which is a type of yeast that undergoes cell division. The fission yeast is widely used in the research of various diseases, including cancer, as it can be used to study the effects of drugs on cell division and to identify potential drug targets.

KIF1A has also been identified as a potential biomarker for various diseases, including cancer. The KIF1A gene has been shown to be expressed in various types of cancer, including breast, lung, and ovarian cancer. Additionally, studies have shown that KIF1A has been associated with cancer progression and the development of cancer-related symptoms. Therefore, KIF1A has the potential to be used as a biomarker for cancer and may be a useful target for new cancer therapies.

In addition to its potential as a drug target and biomarker, KIF1A has also been shown to have a role in the regulation of various physiological processes in the body. For example, KIF1A has been shown to play a critical role in the regulation of cell adhesion, which is the process by which cells stick together to form tissues and organs. Additionally, KIF1A has been shown to regulate the production of carbon dioxide, which is a byproduct of cell metabolism that can have a negative impact on the balance of oxygen and carbon dioxide in the body.

Another study has shown that KIF1A has been associated with the regulation of inflammation. Inflammation is a natural response of the immune system to injury or infection, but chronic inflammation can lead to a host of diseases, including heart disease and neurodegenerative disorders. Therefore, studies have shown that KIF1A plays a critical role in the regulation of inflammation and may be a useful target for new treatments for inflammatory diseases.

In conclusion, KIF1A is a gene that has been identified as a potential drug target and biomarker for various diseases, including diabetes, cancer, and neurodegenerative disorders. Further research is needed to fully understand the role of KIF1A in these diseases and to develop new treatments based on its potential as a drug target and biomarker. By identifying the unique mechanisms by which KIF1A regulates various physiological processes in the body, researchers may be able to develop new treatments that target KIF1A and improve the health and well-being of individuals with various diseases.

Protein Name: Kinesin Family Member 1A

Functions: Motor for anterograde axonal transport of synaptic vesicle precursors (PubMed:33880452). Also required for neuronal dense core vesicles (DCVs) transport to the dendritic spines and axons. The interaction calcium-dependent with CALM1 increases vesicle motility and interaction with the scaffolding proteins PPFIA2 and TANC2 recruits DCVs to synaptic sites

The "KIF1A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about KIF1A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

KIF1B | KIF1C | KIF20A | KIF20B | KIF21A | KIF21B | KIF22 | KIF23 | KIF23-AS1 | KIF24 | KIF25 | KIF25-AS1 | KIF26A | KIF26B | KIF27 | KIF28P | KIF2A | KIF2B | KIF2C | KIF3A | KIF3B | KIF3C | KIF4A | KIF4B | KIF5A | KIF5B | KIF5C | KIF6 | KIF7 | KIF9 | KIF9-AS1 | KIFAP3 | KIFBP | KIFC1 | KIFC2 | KIFC3 | Killer Cell Immunoglobulin-Like Receptor (KIR) | Killer cell immunoglobulin-like receptor 2DS1, transcript variant X1 | KIN | Kinesin-like protein KIF16B (isoform 1) | KIR2DL1 | KIR2DL2 | KIR2DL3 | KIR2DL4 | KIR2DL5A | KIR2DL5B | KIR2DP1 | KIR2DS1 | KIR2DS2 | KIR2DS3 | KIR2DS4 | KIR2DS5 | KIR3DL1 | KIR3DL2 | KIR3DL3 | KIR3DP1 | KIR3DS1 | KIR3DX1 | KIRREL1 | KIRREL1-IT1 | KIRREL2 | KIRREL3 | KIRREL3-AS2 | KIRREL3-AS3 | KISS1 | KISS1R | KIT | KITLG | KIZ | KIZ-AS1 | KL | KLB | KLC1 | KLC2 | KLC3 | KLC4 | KLF1 | KLF10 | KLF11 | KLF12 | KLF13 | KLF14 | KLF15 | KLF16 | KLF17 | KLF17P1 | KLF2 | KLF3 | KLF3-AS1 | KLF4 | KLF5 | KLF6 | KLF7 | KLF8 | KLF9 | KLHDC1 | KLHDC10 | KLHDC2 | KLHDC3 | KLHDC4