CHCHD3: A Protein Associated with HCMV and Potential Drug Or Biomarker

Target Name: CHCHD3

NCBI ID: G54927

CHCHD3

CHCHD3: A Protein Associated with HCMV and Potential Drug Or Biomarker

Human cytomegalovirus (HCMV) is a member of the human herpesvirus family and is present in most individuals worldwide. It is a member of the T-cell positive group and is characterized by the presence of a single copy of the viral genome in the cytoplasm of infected cells. HCMV has been linked to a number of diseases, including cancer, neurodegenerative diseases, and cardiovascular disease.

One of the key challenges in studying HCMV is its ability to evade the host immune system and persist in the body for extended periods of time. Despite advances in our understanding of the virus, many aspects of its pathogenesis and etiology remain poorly understood.

One promising area of research is the study of CHCHD3, a protein that is expressed in the cytoplasm of infected cells and has been shown to be involved in the immune response. CHCHD3 has been shown to interact with a number of different proteins, including the immune response regulator PD-L1.

In recent years, the study of CHCHD3 has been focused on its potential as a drug target or biomarker. There is evidence to suggest that CHCHD3 may be a useful target for cancer treatment, as it has been shown to be involved in the regulation of cell growth and survival.

In addition to its potential as a drug target, CHCHD3 has also been shown to be a useful biomarker for a number of different diseases. For example, it has been shown to be elevated in the blood of individuals with neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. Additionally, it has been shown to be elevated in the blood of individuals with cardiovascular disease, which may be a useful biomarker for this disease.

In conclusion, CHCHD3 is a protein that has the potential to be a drug target or biomarker in the study of HCMV. Further research is needed to fully understand its role in the immune response and its potential as a therapeutic target.

Protein Name: Coiled-coil-helix-coiled-coil-helix Domain Containing 3

Functions: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:25781180)

The "CHCHD3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CHCHD3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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