Potential Drug Target Or Biomarker: CHI3L1 and Its Applications in Disease Treatment

Target Name: CHI3L1

NCBI ID: G1116

CHI3L1

Potential Drug Target Or Biomarker: CHI3L1 and Its Applications in Disease Treatment

CHI3L1 (also known as YK-40), a protein that belongs to the CHI3L1 gene family, has been identified as a potential drug target or biomarker in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

CHI3L1 is a transmembrane protein that is expressed in various tissues and organs, including the brain, spinal cord, heart, and skin. It plays a role in the development and maintenance of the nervous system, and is involved in the regulation of pain, inflammation, and sleep.

Studies have shown that CHI3L1 is involved in a wide range of physiological processes that are important for human health, including the regulation of pain perception and neurogenesis, the regulation of inflammation and immune response, and the regulation of sleep and wakefulness.

One of the key functions of CHI3L1 is its role in pain regulation. CHI3L1 has been shown to play a role in the development and maintenance of pain sensitivity, and is involved in the regulation of pain perception and neurogenesis. This suggests that CHI3L1 may be a potential drug target for pain relief.

Another function of CHI3L1 is its role in neurogenesis. CHI3L1 has been shown to play a role in the development and maintenance of neural stem cells, and is involved in the regulation of neural stem cell proliferation and differentiation. This suggests that CHI3L1 may be a potential drug target for neurogenesis, and for the treatment of neurodegenerative diseases.

CHI3L1 is also involved in the regulation of inflammation and immune response. It has been shown to play a role in the regulation of inflammation and immune cell function, and is involved in the regulation of the immune response to infection. This suggests that CHI3L1 may be a potential drug target for the treatment of autoimmune disorders and other inflammatory conditions.

In addition to its involvement in pain, neurogenesis, and inflammation, CHI3L1 is also involved in the regulation of sleep and wakefulness. It has been shown to play a role in the regulation of sleep and wakefulness, and is involved in the development of sleep disorders. This suggests that CHI3L1 may be a potential drug target for the treatment of sleep disorders.

Overall, CHI3L1 is a protein that is involved in a wide range of physiological processes that are important for human health. As a potential drug target or biomarker, CHI3L1 has the potential to be used for the treatment of a wide range of conditions, including cancer, neurodegenerative diseases, and autoimmune disorders. Further research is needed to fully understand the role of CHI3L1 in human health and to develop effective treatments.

Protein Name: Chitinase 3 Like 1

Functions: Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung

The "CHI3L1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CHI3L1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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