Target Name: CHN1
NCBI ID: G1123
Review Report on CHN1 Target / Biomarker Content of Review Report on CHN1 Target / Biomarker
CHN1
Other Name(s): chimerin (chimaerin) 1 | NC | Rho GTPase-activating protein 2 | CHN | chimerin 1 | N-chimaerin (isoform 3) | A-chimaerin | Alpha-chimerin | DURS2 | Chimerin 1, transcript variant 2 | N-chimaerin (isoform 2) | N-chimerin | CHN1 variant 2 | RHOGAP2 | alpha-chimerin | ARHGAP2 | chimaerin 1 | n-chimerin | CHIN_HUMAN | Chimerin 1 (GTPase-activating protein, rho, 2) | a2-chimaerin | CHN1 variant 3 | N-chimaerin | Chimerin 1, transcript variant 3

CHN1: A Potential Drug Target and Biomarker for Cancer

CHN1, also known as chimerin-1, is a protein that is expressed in various tissues throughout the body. It is a key regulator of cell proliferation and has been identified as a potential drug target in the treatment of various diseases, including cancer.

CHN1 is a transmembrane protein that is involved in the TGF-β signaling pathway, which is a critical pathway that regulates cell growth, differentiation, and survival. The TGF-β pathway is a complex signaling pathway that is involved in the development and maintenance of tissues and organs, and is a key factor in the development of many diseases, including cancer.

Studies have identified CHN1 as a potential drug target in the treatment of various diseases, including cancer. For example, studies have shown that inhibiting the activity of CHN1 has anti-tumor effects in various cancer models, including breast, lung, and colorectal cancer.

In addition to its potential as a drug target, CHN1 has also been identified as a biomarker for the diagnosis and prognosis of cancer. For example, studies have shown that decreased levels of CHN1 have been associated with poor prognosis in patients with breast cancer, and that higher levels of CHN1 are associated with poor prognosis in patients with colorectal cancer.

The identification of CHN1 as a potential drug target and biomarker has led to a greater understanding of its role in the development and progression of cancer. Further research is needed to fully understand the mechanisms of CHN1's involvement in cancer and to develop effective treatments.

In conclusion, CHN1 is a protein that has been identified as a potential drug target and biomarker in the treatment of various diseases, including cancer. Further research is needed to fully understand its role in cancer development and to develop effective treatments.

Protein Name: Chimerin 1

Functions: GTPase-activating protein for p21-rac and a phorbol ester receptor. Involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance

The "CHN1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CHN1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

CHN2 | CHN2-AS1 | CHODL | Cholesterol Epoxide Hydrolase (ChEH) | Cholesterol esterase | Choline transporter-like protein | CHORDC1 | CHORDC1P4 | CHP1 | CHP1P2 | CHP2 | CHPF | CHPF2 | CHPT1 | CHRAC1 | CHRD | CHRDL1 | CHRDL2 | CHRFAM7A | CHRM1 | CHRM2 | CHRM3 | CHRM3-AS2 | CHRM4 | CHRM5 | CHRNA1 | CHRNA10 | CHRNA2 | CHRNA3 | CHRNA4 | CHRNA5 | CHRNA6 | CHRNA7 | CHRNA9 | CHRNB1 | CHRNB2 | CHRNB3 | CHRNB4 | CHRND | CHRNE | CHRNG | Chromobox protein homolog | Chromodomain Helicase DNA Binding Protein | Chromosome 10 open reading frame 115 | Chromosome 16 open reading frame 47 | Chromosome 17 open reading frame 47 | Chromosome 6 open reading frame 183 | CHROMR | CHST1 | CHST10 | CHST11 | CHST12 | CHST13 | CHST14 | CHST15 | CHST2 | CHST3 | CHST4 | CHST5 | CHST6 | CHST7 | CHST8 | CHST9 | CHSY1 | CHSY3 | CHTF18 | CHTF8 | CHTOP | CHUK | CHURC1 | CHURC1-FNTB | Chymotrypsin | CIAO1 | CIAO2A | CIAO2AP2 | CIAO2B | CIAO3 | CIAPIN1 | CIART | CIB1 | CIB2 | CIB3 | CIB4 | CIBAR1 | CIBAR1-DT | CIBAR1P1 | CIBAR1P2 | CIBAR2 | CIC | CICP10 | CICP11 | CICP17 | CICP25 | CICP5 | CICP7 | CIDEA | CIDEB | CIDEC | CIDECP1 | CIITA