SMG8: A Non-Coding RNA Molecule with Potential as A Drug Target and Biomarker

Target Name: SMG8

NCBI ID: G55181

SMG8

SMG8: A Non-Coding RNA Molecule with Potential as A Drug Target and Biomarker

SMG8, also known as C17orf71, is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various diseases, including cancer. Its unique structure and function have made it an attractive target for researchers to study and develop new treatments.

SMG8 is a small non-coding RNA molecule that is approximately 200 nucleotides long. It is expressed in a variety of tissues and cells in the body and is involved in the regulation of gene expression. Studies have shown that SMG8 can interact with various proteins and can also act as a protein in some cases.

One of the key features of SMG8 is its unique structure. It has a characteristic hairpin-like shape and is composed of a series of alternating double-stranded and single-stranded regions. This structure makes it difficult to study and understand its function, but it is thought to play a role in the regulation of gene expression and the control of cellular processes.

SMG8 has also been shown to interact with a variety of proteins, including transcription factors, DNA-binding proteins, and proteins involved in the regulation of RNA stability. These interactions suggest that SMG8 may be involved in the regulation of gene expression and the expression of various genetic information.

In addition to its structural features, SMG8 has also been shown to play a role in the regulation of cellular processes. Studies have shown that SMG8 can interact with and influence the activity of various proteins involved in cell adhesion, migration, and the regulation of the cytoskeleton. This suggests that SMG8 may be involved in the regulation of cellular movement and the maintenance of cell structure.

SMG8 has also been shown to be involved in the regulation of stem cell proliferation and differentiation. Studies have shown that SMG8 can interact with and influence the activity of various proteins involved in the regulation of stem cell proliferation and differentiation, including the factors that promote stem cell growth and the factors that inhibit stem cell proliferation. This suggests that SMG8 may be involved in the regulation of stem cell behavior and the development of tissues and organs.

In addition to its potential involvement in drug development and cancer research, SMG8 may also be a useful biomarker for the diagnosis and treatment of various diseases. Studies have shown that SMG8 can be expressed in a variety of tissues and cells in the body and that it is involved in the regulation of gene expression in these tissues. This suggests that SMG8 may be a useful biomarker for the diagnosis and treatment of various diseases, including cancer.

In conclusion, SMG8 is a non-coding RNA molecule that has unique structural features and is involved in the regulation of gene expression and cellular processes. Its potential as a drug target and biomarker for various diseases makes it an attractive target for researchers to study and develop new treatments. Further research is needed to fully understand the role of SMG8 in these processes and to determine its potential as a drug or biomarker.

Protein Name: SMG8 Nonsense Mediated MRNA Decay Factor

Functions: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity

The "SMG8 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SMG8 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets