Targeting NB5 for Neuroblastoma Treatment (G50651)

Target Name: SLC45A1

NCBI ID: G50651

SLC45A1

Targeting NB5 for Neuroblastoma Treatment

SLC45A1 is a gene that encodes a protein known as neuroblastoma 5 (NB5). NB5 is a protein that is expressed in various tissues throughout the body, including the brain, and is involved in the development and progression of neuroblastomas.

Studies have shown that NB5 plays a crucial role in the development and progression of neuroblastomas, as well as in the survival of neuroblastoma cells. NB5 has also been shown to interact with several other proteins, including the protein PDGF-BB.

As a result of its involvement in the development and progression of neuroblastomas, NB5 has been identified as a potential drug target for the treatment of neuroblastomas. Researchers have been exploring the use of drugs that can specifically target NB5 to treat neuroblastomas.

One approach to targeting NB5 is to use small molecules that can inhibit the activity of NB5. These small molecules can be designed to specifically target the active site of NB5, which is thought to be located on the protein.

Another approach to targeting NB5 is to use antibodies that can specifically recognize and target the protein NB5. These antibodies can be used to deliver a payload of drugs directly to NB5-positive cells, such as chemotherapy drugs or targeted therapies.

In addition to its potential as a drug target, NB5 has also been identified as a potential biomarker for the diagnosis and prognosis of neuroblastomas. Studies have shown that the expression of NB5 is significantly increased in neuroblastoma tissues compared to non-neuroblastoma tissues.

In addition, NB5 has been shown to be involved in the formation of neuroblastoma cells, as well as in the maintenance of neuroblastoma cell survival. This suggests that NB5 may play a key role in the development and progression of neuroblastomas.

Overall, the study of SLC45A1 (Deleted in neuroblastoma 5 protein) has shown to be a promising target for the treatment of neuroblastomas. Further research is needed to fully understand the role of NB5 in the development and progression of neuroblastomas, as well as to develop effective treatments for these devastating diseases.

Protein Name: Solute Carrier Family 45 Member 1

Functions: Proton-associated glucose transporter in the brain

The "SLC45A1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLC45A1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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