VAC14: Regulating Neuronal Excitability and Synaptic Strength in Neural Development

Target Name: VAC14

NCBI ID: G55697

VAC14

VAC14: Regulating Neuronal Excitability and Synaptic Strength in Neural Development

VAC14 (Protein VAC14 homolog) is a protein that is expressed in various cell types, including neurons and glial cells in the central nervous system. It is a member of the Vacillator protein family, which is known for their ability to regulate cell growth, differentiation, and survival.

One of the unique aspects of VAC14 is its ability to interact with several different proteins, including the neurotransmitter GABA. This interaction between VAC14 and GABA has been shown to play a role in a variety of physiological processes, including neuronal signaling, synaptic plasticity, and stress response.

In addition to its interaction with GABA, VAC14 has also been shown to interact with several other proteins, including the transcription factor NF-kappa-B. This interaction between VAC14 and NF-kappa-B has been shown to play a role in the regulation of gene expression and cellular processes such as cell growth, migration, and differentiation.

The vacillator gene has been identified and the protein Vacillator-14 (VAC14) has been shown to have a variety of functions in neural development, including the regulation of neuronal excitability and the modulation of synaptic strength.

One of the most interesting features of VAC14 is its ability to form a complex with the protein synaptophysin, which is a protein that plays a central role in synaptic structure and function. This complex formation has been shown to play a role in the regulation of synaptic strength and the modulation of neuronal excitability.

In addition to its role in synaptic structure and function, VAC14 has also been shown to play a role in the regulation of cellular processes such as cell growth, apoptosis, and inflammation.

The vacillator gene has been identified and the protein Vacillator-14 (VAC14) has been shown to have a variety of functions in neural development, including the regulation of neuronal excitability and the modulation of synaptic strength.

One of the most interesting features of VAC14 is its ability to form a complex with the protein synaptophysin, which is a protein that plays a central role in synaptic structure and function. This complex formation has been shown to play a role in the regulation of synaptic strength and the modulation of neuronal excitability.

In addition to its role in synaptic structure and function, VAC14 has also been shown to play a role in the regulation of cellular processes such as cell growth, apoptosis, and inflammation.

VAC14 has also been shown to play a role in the regulation of neuronal excitability, which is important for the function of the nervous system. The regulation of neuronal excitability is critical for the proper functioning of the nervous system, and alterations in this regulation have been linked to a variety of neurological and psychiatric disorders.

In addition to its role in the regulation of neuronal excitability, VAC14 has also been shown to play a role in the regulation of cellular processes such as cell growth, apoptosis, and inflammation.

It is also interesting to note that VAC14 has been shown to play a role in the regulation of synaptic plasticity, which is the ability of the nervous system to change and adapt in response to experience. This regulation of synaptic plasticity is critical for the development and maintenance of normal neural function.

The vacillator gene has been identified and the protein Vacillator-14 (VAC14) has been shown to have a variety of functions in neural development, including the regulation of neuronal excitability and the modulation of synaptic strength.

One of the most interesting features of VAC14 is its ability to form a complex with the protein synaptophysin

Protein Name: VAC14 Component Of PIKFYVE Complex

Functions: Scaffold protein component of the PI(3,5)P2 regulatory complex which regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Pentamerizes into a star-shaped structure and nucleates the assembly of the complex. The pentamer binds a single copy each of PIKFYVE and FIG4 and coordinates both PIKfyve kinase activity and FIG4 phosphatase activity, being required to maintain normal levels of phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 5-phosphate (PtdIns(5)P) (PubMed:33098764). Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes

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•   expression level;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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