PRL: A Protein Regulator of Milk Production and Secretion (G5618)

Target Name: PRLR

NCBI ID: G5618

PRLR

PRL: A Protein Regulator of Milk Production and Secretion

Prolactin (PRL) is a protein produced by the human body that plays a critical role in milk production and secretion. It is a large transmembrane protein that consists of four distinct chains A, B, C, and D. PRL is highly conserved across various species, and it has been implicated in various physiological processes, including milk production, lactation, and pregnancy.

One of the key functions of PRL is its ability to interact with other proteins, particularly the protein called secreted prolactin (SPL). SPL is a protein produced by the pituitary gland that plays a critical role in milk production and secretion. It is a small transmembrane protein that consists of two chains A and B.

The interaction between PRL and SPL has been extensively studied, and it is known that PRL can bind to SPL with high affinity. This interaction between PRL and SPL is critical for the regulation of milk production and secretion.

PRL has been shown to play a key role in the regulation of milk production and secretion. It is well established that PRL is a critical regulator of milk letdown, which is the process by which milk is released from the breast during breastfeeding. PRL has been shown to interact with SPL and regulate its activity.

In addition to its role in milk production and secretion, PRL is also involved in the regulation of pregnancy. During pregnancy, PRL is produced in the human placenta and has been shown to play a critical role in the regulation of pregnancy outcomes.

PRL has also been shown to be involved in various signaling pathways. For example, it has been shown to be involved in the FGF signaling pathway, which is a critical pathway involved in cell growth, differentiation, and angiogenesis. PRL has also been shown to be involved in the TGF-β signaling pathway, which is involved in cell growth, differentiation, and cell-cell signaling.

In conclusion, PRL is a protein that plays a critical role in various physiological processes, including milk production and secretion, pregnancy, and signaling pathways. Its interaction with SPL is critical for the regulation of these processes. As a result, PRL is an attractive drug target and could be useful in the development of new therapies for various diseases.

Protein Name: Prolactin Receptor

Functions: This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling

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•   general information;
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•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
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•   related combination drugs;
•   pharmacochemistry experiments;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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