NFE4: A Potential Drug Target Or Biomarker (G58160)

Target Name: NFE4

NCBI ID: G58160

NFE4

NFE4: A Potential Drug Target Or Biomarker

Nuclear factor, erythroid 4 (NFE4) is a protein that plays a crucial role in regulating the function of the thyroid gland. It is a key component of the thyroid hormone, which is responsible for regulating metabolism, growth, and development. NFE4 is a protein that is expressed in high levels in the thyroid gland and has been identified as a potential drug target or biomarker.

The thyroid gland is a small organ located at the base of the neck that is responsible for producing thyroid hormones. These hormones are responsible for regulating the body's metabolism, growth, and development. They are produced by the thyroid gland's cells, which are specialized cells called T cells. The T cells are a type of white blood cell that are responsible for carrying out a variety of functions in the body, including fighting off infections and helping the body to adapt to changes in the environment.

NFE4 is a protein that is expressed in high levels in the thyroid gland. It is made up of four amino acids, which are the building blocks of proteins. The first amino acid in NFE4 is cysteine, which is a sulfur-containing amino acid that is important for the structure and function of proteins. The second amino acid is glutamic acid, which is a type of amino acid that is involved in the transfer of electrical signals in the body. The third amino acid is alanine, which is an amino acid that is involved in the structure and function of proteins. The fourth amino acid in NFE4 is serine, which is a sulfur-containing amino acid that is important for the structure and function of proteins.

NFE4 is involved in regulating the function of the thyroid gland by participating in a variety of important processes. For example, it is involved in the production of thyroid hormones, which are responsible for regulating the body's metabolism, growth, and development. NFE4 is also involved in regulating the function of the thyroid gland's cells, which are specialized cells that are responsible for producing thyroid hormones.

In addition to its role in regulating the function of the thyroid gland, NFE4 has also been identified as a potential drug target or biomarker. Researchers have found that NFE4 is expressed in high levels in the thyroid gland and that it is involved in the production of thyroid hormones. This suggests that NFE4 could be a useful target for drugs that are designed to treat thyroid gland disorders.

NFE4 has also been shown to be involved in a variety of other processes in the body. For example, it is involved in the regulation of the immune system, which is responsible for fighting off infections and protecting the body against harmful substances. It is also involved in the regulation of the blood sugar levels, which is important for maintaining the body's energy levels.

In conclusion, NFE4 is a protein that is expressed in high levels in the thyroid gland and has been identified as a potential drug target or biomarker. It is involved in regulating the function of the thyroid gland and is also involved in a variety of other processes in the body. Further research is needed to fully understand the role of NFE4 in the regulation of the thyroid gland and its potential as a drug target or biomarker.

Protein Name: Nuclear Factor, Erythroid 4

Functions: Functions as part of the SSP (stage selector protein) complex, a complex that contributes to the preferential expression of the gamma-gene in fetal erythroid cells by facilitating the interaction of the gamma-globin genes with enhancer elements contained in the locus control region (LCR). The complex binds to the stage selector element (SSE) in the proximal gamma-globin promoter. In contrast, isoform 2 acts as a repressor of gamma-globin gene expression by preventing NFE2 and RNA polymerase II recruitment to the promoter

The "NFE4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NFE4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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