Study of NITRILASE 1: Clinical Significance and Drug Targets (G4817)

Target Name: NIT1

NCBI ID: G4817

NIT1

Study of NITRILASE 1: Clinical Significance and Drug Targets

NITRILASE 1 (N1) is a protein that is expressed in various cell types, including muscle, nerve, and heart cells. N1 is a key enzyme that participates in many important metabolic pathways in cells, including cellular respiration, cell division, Cell growth and apoptosis, etc. In addition, N1 is also involved in the process of cell signaling and plays an important role in neural development and regeneration.

In recent years, researchers have discovered that N1 plays an important role in many diseases, such as cancer, diabetes, heart disease, stroke, and neurodegenerative diseases. In addition, N1 is also related to the efficacy and toxicity of many drugs. Therefore, studying N1 as a drug target or biomarker has important clinical significance.

As a drug target, N1 has been used to treat a variety of diseases. For example, N1 inhibitors can inhibit the respiration of cancer cells, thereby inhibiting the growth of cancer cells. N1 inhibitors can also be used to treat neurodegenerative diseases, such as Parkinson's disease, Alzheimer's disease, and Alzheimer's disease.

As a biomarker, N1 can be used to detect the development and treatment effects of many diseases. For example, by measuring the level of N1 in the blood, the effectiveness of drug treatment in patients with Parkinson's disease can be evaluated. N1 can also be used as a biomarker of myocardial damage to detect the extent of myocardial damage.

N1 is also associated with the toxicity of many drugs. For example, some antihypertensive drugs may inhibit the activity of N1, resulting in reduced efficacy of the drug. Therefore, researchers need to detect the activity of N1 to ensure the safety and effectiveness of the drug.

N1 plays an important role in many diseases, so studying N1 as a drug target or biomarker has important clinical significance. As technology continues to advance, studying N1 will provide us with more treatments and diagnostics to better treat many diseases.

Protein Name: Nitrilase 1

Functions: Catalyzes the hydrolysis of the amide bond in N-(4-oxoglutarate)-L-cysteinylglycine (deaminated glutathione), a metabolite repair reaction to dispose of the harmful deaminated glutathione. Plays a role in cell growth and apoptosis: loss of expression promotes cell growth, resistance to DNA damage stress and increased incidence to NMBA-induced tumors. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells

The "NIT1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NIT1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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