Target Name: NIPA1
NCBI ID: G123606
Review Report on NIPA1 Target / Biomarker Content of Review Report on NIPA1 Target / Biomarker
NIPA1
Other Name(s): non imprinted in Prader-Willi/Angelman syndrome 1 | Magnesium transporter NIPA1 (isoform 1) | MGC35570 | NIPA magnesium transporter 1 | Non-imprinted in Prader-Willi/Angelman syndrome region protein 1 | Spastic paraplegia 6 (autosomal dominant) | NIPA1_HUMAN | spastic paraplegia 6 protein | non-imprinted in Prader-Willi/Angelman syndrome region protein 1 | Spastic paraplegia 6 protein | SLC57A1 | SPG6 | Non imprinted in Prader-Willi/Angelman syndrome 1 | FSP3 | NIPA1 variant 1 | Magnesium transporter NIPA1 | NIPA magnesium transporter 1, transcript variant 1

NIPA1 as A Potential Drug Target for PIPA Syndrome

NIPA1 (Non-Invasive Positive Pressure Airway Pressure) is a molecule that is expressed in the airways of individuals with Non-Invasive Positive Pressure Airway Pressure (PIPA) syndrome, also known as Prader-Willi syndrome or Angelman syndrome. This condition is characterized by the development of abnormalities in the airway, including a broadening of the airways, an increase in the number of airway turbulence, and a reduction in airway resistance.

Recent studies have identified NIPA1 as a potential drug target for the treatment of PIPA syndrome. The underlying cause of this condition is the loss of normal airway function, which can lead to a range of respiratory problems, including chronic obstructive pulmonary disease (COPD), asthma, and even death. By targeting NIPA1, researchers hope to improve airway function and alleviate the symptoms of PIPA syndrome.

One of the main challenges in studying NIPA1 and its potential role in PIPA syndrome is its expression and function in the airways of individuals with the condition. Currently, there are few reliable methods for detecting the expression of NIPA1 in the airways of individuals with PIPA syndrome. However, researchers have found that NIPA1 is expressed in the airways of individuals with PIPA syndrome, and that it is involved in the regulation of airway smooth muscle function.

Another challenge is understanding the underlying molecular mechanisms that govern the development and progression of PIPA syndrome. While researchers have identified several potential targets for the treatment of PIPA syndrome, including NIPA1, they are still working to fully understand the role of this molecule in the development and progression of the condition.

Despite these challenges, researchers are hopeful that they will be able to use NIPA1 as a drug target to treat PIPA syndrome. The potential benefits of such a treatment would be significant, as PIPA syndrome can be a life-threatening condition that affects millions of people worldwide. By targeting NIPA1, researchers hope to improve airway function and alleviate the symptoms of PIPA syndrome, and ultimately, to improve the quality of life for individuals with this condition.

In conclusion, NIPA1 is a molecule that has been identified as a potential drug target for the treatment of PIPA syndrome. While there are still many challenges that need to be overcome, researchers are hopeful that they will be able to use NIPA1 as a means of treating this life-threatening condition. Further research is needed to fully understand the role of NIPA1 in the development and progression of PIPA syndrome, and to determine its effectiveness as a drug target.

Protein Name: NIPA Magnesium Transporter 1

Functions: Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity)

The "NIPA1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NIPA1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

NIPA2 | NIPAL1 | NIPAL2 | NIPAL3 | NIPAL4 | NIPBL | NIPBL-DT | NIPSNAP1 | NIPSNAP2 | NIPSNAP3A | NIPSNAP3B | NISCH | NIT1 | NIT2 | Nitric oxide synthase (NOS) | NKAIN1 | NKAIN1P1 | NKAIN2 | NKAIN3 | NKAIN4 | NKAP | NKAPD1 | NKAPL | NKAPP1 | NKD1 | NKD2 | NKG7 | NKILA | NKIRAS1 | NKIRAS2 | NKPD1 | NKRF | NKTR | NKX1-1 | NKX1-2 | NKX2-1 | NKX2-1-AS1 | NKX2-2 | NKX2-3 | NKX2-4 | NKX2-5 | NKX2-6 | NKX2-8 | NKX3-1 | NKX3-2 | NKX6-1 | NKX6-2 | NKX6-3 | NLE1 | NLGN1 | NLGN1-AS1 | NLGN2 | NLGN3 | NLGN4X | NLGN4Y | NLK | NLN | NLRC3 | NLRC4 | NLRC4 Inflammasome | NLRC5 | NLRP1 | NLRP1 Inflammasome | NLRP10 | NLRP11 | NLRP12 | NLRP13 | NLRP14 | NLRP2 | NLRP2B | NLRP3 | NLRP3 Inflammasome | NLRP3P1 | NLRP4 | NLRP5 | NLRP6 | NLRP7 | NLRP8 | NLRP9 | NLRP9P1 | NLRX1 | NMB | NMBR | NMD3 | NMDA receptor | NME1 | NME1-NME2 | NME2 | NME2P1 | NME3 | NME4 | NME5 | NME6 | NME7 | NME8 | NME9 | NMI | NMNAT1 | NMNAT2 | NMNAT3