SLN: A Protein Involved in Pain Perception and Neuroinflammation

Target Name: SLN

NCBI ID: G6588

Content of Review Report on SLN Target / Biomarker

SLN

Other Name(s): sarcolipin | Sarcolipin | SARCO_HUMAN

SLN: A Protein Involved in Pain Perception and Neuroinflammation

SLN (sinovial membrane-associated protein) is a protein that is expressed in the endoplasmic reticulum (ER) and is involved in several cellular processes, including cell signaling, migration, and invasion. It has also been shown to be involved in pain perception and neuroinflammation. SLN has been identified as a potential drug target and has the potential to treat various diseases.

SLN is a transmembrane protein that is composed of two main regions: an extracellular region (ECR) and an intracellular region (ICR). The ECR is involved in SLN's ability to interact with other proteins and molecules, including cytoplasmic proteins and signaling molecules. The ICR is responsible for SLN's ability to interact with the endoplasmic reticulum and for its localization to the ER.

SLN has been shown to play a role in several cellular processes, including cell signaling, migration, and invasion. For example, SLN has been shown to be involved in the regulation of T cell development and function. SLN has also been shown to be involved in the regulation of cell migration and the development of cancer.

SLN has also been shown to be involved in pain perception and neuroinflammation. For example, SLN has been shown to play a role in the development of pain-related neuroinflammation in the brain. This suggests that SLN may be a potential drug target for the treatment of chronic pain.

In addition to its role in pain perception and neuroinflammation, SLN has also been shown to be involved in the regulation of cellular signaling pathways. For example, SLN has been shown to be involved in the regulation of the production of reactive oxygen species (ROS), which can damage cellular components and contribute to the development of neurodegenerative diseases.

SLN has also been shown to be involved in the regulation of cellular signaling pathways related to cell growth and survival. For example, SLN has been shown to be involved in the regulation of the production of cell cycle proteins, which are responsible for the cell cycle and the regulation of cell growth and survival.

In conclusion, SLN is a protein that is involved in several cellular processes, including cell signaling, migration, and invasion. It has also been shown to be involved in pain perception and neuroinflammation. As a potential drug target, SLN has the potential to treat various diseases, including chronic pain, neurodegenerative diseases, and cancer. Further research is needed to fully understand the role of SLN in these diseases and to develop effective treatments.

Protein Name: Sarcolipin

Functions: Reversibly inhibits the activity of ATP2A1 and ATP2A2 in sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in muscle. Required for muscle-based, non-shivering thermogenesis (By similarity)

The "SLN Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLN comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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