Study: STK10: Key Regulator of Human Stress Response (G6793)

Target Name: STK10

NCBI ID: G6793

STK10

Study: STK10: Key Regulator of Human Stress Response

STK10 (STK10_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, spleen, and muscle. It is a key regulator of the stress response and has been implicated in a number of cellular processes that are important for human health and disease.

One of the key functions of STK10 is its role in the stress response. When the body experiences stress, STK10 helps to regulate the signaling pathways that are activated to cope with the stress. This is important for maintaining the homeostasis of the body and for ensuring that the body is able to withstand and recover from stress-induced damage.

In addition to its role in the stress response, STK10 is also involved in a number of other cellular processes that are important for human health and disease. For example, STK10 has been shown to be involved in the regulation of cell growth, differentiation, and survival. It has also been implicated in the development and progression of a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

As a drug target, STK10 is of particular interest to researchers because of its involvement in a number of important cellular processes. This makes it an attractive target for drugs that are designed to modulate its activity and improve the health and treatment outcomes of human disease.

One of the key challenges in studying STK10 is its complex biology. Because it is involved in many different cellular processes, from cell growth to apoptosis, the functions and interactions of STK10 are very complex. Therefore, studying STK10 requires the use of multiple methods, including gene knockout, overexpression, co-transfection, and co-precipitation.

In drug research, STK10 is also of high value as a drug target. Currently, there are some drugs that have shown intervention effects on STK10 in preclinical studies. These drugs include inhibitors of STK10 activators, such as NEDD8A agonists and STK10 antagonists.

In addition, researchers are exploring the potential of STK10 as a therapeutic strategy. For example, STK10 inhibitors have been shown to extend lifespan, improve cognitive function, and enhance exercise capacity in mice. In addition, STK10 overexpression has also been shown to increase the survival of nerve cells and improve neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

Overall, STK10 is a promising drug target that has attracted extensive research interest. As research deepens, people will continue to reveal the function of STK10 in cell biology and its potential as a drug target to improve human health.

Protein Name: Serine/threonine Kinase 10

Functions: Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo

The "STK10 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about STK10 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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