ENTPD1-AS1: A Potential Drug Target and Biomarker (G728558)

Target Name: ENTPD1-AS1

NCBI ID: G728558

ENTPD1-AS1

Other Name(s): ENTPD1 antisense RNA 1 | ENTPD1 antisense RNA 1, transcript variant 1 | ENTPD1-AS1 variant 1

ENTPD1-AS1: A Potential Drug Target and Biomarker

ENTPD1-AS1, also known as ENTPD1-AS1 antigen, is a protein that is expressed in various tissues of the body, including the brain, heart, lungs, and gastrointestinal tract. It is a member of the ENTPD1 family, which is characterized by the presence of a specific RNA structure, called the exon-intron retention domain (ExID), in the protein sequence.

The ExID is a unique feature that allows ENTPD1 proteins to form a heterodimer with each other, which can lead to the formation of functional RNA-protein complexes. These complexes are involved in various cellular processes, including cell signaling, protein-protein interactions, and RNA regulation.

ENTPD1-AS1 is a 21-kDa protein that is expressed in the brain, heart, lungs, and gastrointestinal tract. It is highly expressed in the brain, where it is found in the basal ganglia, which is responsible for the coordination of motor movements, as well as in the cardiac muscle, where it is involved in the regulation of contractions.

The ENTPD1-AS1 protein has been shown to play a role in various physiological processes, including neuronal signaling, muscle contractions, and cell survival. It is involved in the regulation of several signaling pathways, including the cAMP/cGMP signaling pathway, the PI3K/AKT signaling pathway, and the TGF-β signaling pathway.

In addition to its role in cellular signaling, ENTPD1-AS1 is also potential drug target. The protein is highly expressed in various tissues of the body, including the brain, heart, and gastrointestinal tract, which makes it an attractive target for small molecule inhibitors.

ENTPD1-AS1 has been shown to interact with several small molecules, including inhibitors of the tyrosine kinase activity of the protein itself. These interactions suggest that ENTPD1-AS1 may be a drug target that can be targeted by small molecules.

The ENTPD1-AS1 protein has also been shown to interact with several biomarkers, including the protein brain-derived neurotrophic factor (BDNF), which is a protein that is involved in the regulation of brain function and is often used as a biomarker for neurodegenerative diseases.

The interaction between ENTPD1-AS1 and BDNF suggests that ENTPD1-AS1 may be a drug target that can be targeted by small molecules or antibodies that target the protein itself.

In conclusion, ENTPD1-AS1 is a protein that is expressed in various tissues of the body and is involved in various cellular processes, including neuronal signaling, muscle contractions, and cell survival. It is also a potential drug target due to its high expression in the brain and its interaction with small molecules and biomarkers. Further research is needed to fully understand the role of ENTPD1-AS1 in cellular signaling and its potential as a drug target.

Protein Name: ENTPD1 Antisense RNA 1

The "ENTPD1-AS1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ENTPD1-AS1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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