Target Name: SHISA7
NCBI ID: G729956
Review Report on SHISA7 Target / Biomarker Content of Review Report on SHISA7 Target / Biomarker
SHISA7
Other Name(s): Protein shisa-7 | protein shisa-7 | CKAMP59 | Protein shisa-6-like | GABA(A) receptor auxiliary subunit Shisa7 | shisa family member 7 | UPF0626 protein A | shisa homolog 7 | Cystine-knot AMPAR modulating protein of 59 kDa | cystine-knot AMPAR modulating protein of 59 kDa | SHSA7_HUMAN | Shisa family member 7

SHISA7: A Potential Drug Target and Biomarker

Shisa7, also known as protein shisa-7, is a protein that is expressed in various tissues of the body, including the liver, spleen, and lungs. It is a member of the Shisa family, which includes several similar proteins that play important roles in the immune response and inflammation. One of the unique features of shisa7 is its potential as a drug target and biomarker.

The immune response is a critical mechanism that helps the body fight off infections and diseases. The immune system consists of various types of white blood cells, including T cells, B cells, and natural killer cells, which work together to identify and destroy foreign particles in the body. Shisa7 plays a key role in this process by regulating the activity of natural killer cells, which are a crucial part of the immune response.

Shisa7 is a protein that is known to interact with the immune system in various ways. For example, it has been shown to interact with the T-cell receptor, which is a key component of the immune response. This interaction between shisa7 and the T -cell receptor suggests that shisa7 may be a potential drug target for treating immune-related diseases.

In addition to its role in the immune response, shisa7 is also a potential biomarker for several types of diseases. For example, studies have shown that shisa7 levels are elevated in individuals with certain types of cancer, which suggests that it may be a useful biomarker for cancer diagnosis and treatment.

Another potential use for shisa7 is as a therapeutic agent for treating autoimmune diseases. Autoimmune diseases occur when the immune system attacks the body's own tissues, leading to a range of symptoms and conditions. Shisa7 has been shown to have anti-inflammatory effects, which may make it a useful treatment for autoimmune diseases.

In conclusion, shisa7 is a protein that has the potential to be a drug target and biomarker for a variety of diseases. Its interaction with the immune system and its potential as a therapeutic agent make it an attractive target for further research and development. Further studies are needed to fully understand the role of shisa7 in the immune response and its potential as a drug and biomarker.

Protein Name: Shisa Family Member 7

Functions: Transmembrane protein that regulates gamma-aminobutyric acid type A receptor (GABA(A)R) trafficking, channel deactivation kinetics and pharmacology, necessary for fast inhibitory transmission in the brain. Enhances the action of benzodiazepine, a primary GABA(A)Rs target drug, in the brain. May affect channel kinetics of AMPA-type glutamate receptors (AMPAR), the brain's main excitatory neurotransmitter, necessary for synaptic hippocampal plasticity, and memory recall. May regulate the induction and maintenance of long-term potentiation at Schaffer collaterals/CA3-CA1 excitatory synapses

The "SHISA7 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SHISA7 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

SHISA8 | SHISA9 | SHISAL1 | SHISAL2A | SHISAL2B | SHKBP1 | SHLD1 | SHLD2 | SHLD2P1 | SHLD2P3 | SHLD3 | SHMT1 | SHMT2 | SHOC1 | SHOC2 | Short transient receptor potential channel (TrpC) | SHOX | SHOX2 | SHPK | SHPRH | SHQ1 | SHROOM1 | SHROOM2 | SHROOM3 | SHROOM4 | SHTN1 | SI | SIAE | SIAH1 | SIAH2 | SIAH3 | Sialidase | Sialyltransferase | SIDT1 | SIDT2 | SIGIRR | SIGLEC1 | SIGLEC10 | SIGLEC11 | SIGLEC12 | SIGLEC14 | SIGLEC15 | SIGLEC16 | SIGLEC17P | SIGLEC5 | SIGLEC6 | SIGLEC7 | SIGLEC8 | SIGLEC9 | SIGLECL1 | sigma Receptor | SIGMAR1 | Signal peptidase complex | Signal recognition particle | Signal recognition particle receptor | Signal Transducers and Activators of Transcription (STAT) | SIK1 | SIK2 | SIK3 | SIKE1 | SIL1 | SILC1 | SIM1 | SIM2 | SIMC1 | SIN3 complex | SIN3A | SIN3B | SINHCAF | SIPA1 | SIPA1L1 | SIPA1L1-AS1 | SIPA1L2 | SIPA1L3 | SIRPA | SIRPAP1 | SIRPB1 | SIRPB2 | SIRPB3P | SIRPD | SIRPG | SIRPG-AS1 | SIRT1 | SIRT2 | SIRT3 | SIRT4 | SIRT5 | SIRT6 | SIRT7 | SIT1 | SIVA1 | SIX1 | SIX2 | SIX3 | SIX3-AS1 | SIX4 | SIX5 | SIX6 | SKA1 | SKA1 complex