Target Name: MCPH1
NCBI ID: G79648
Review Report on MCPH1 Target / Biomarker Content of Review Report on MCPH1 Target / Biomarker
MCPH1
Other Name(s): truncated microcephalin | BRCT-repeat inhibitor of TERT expression 1 | Microcephalin 1, transcript variant 1 | microcephalin 1 | Microcephalin isoform 1 | Microcephalin | MCPH1 variant 1 | MCPH1_HUMAN | BRIT1 | MCT

MCPH1: A Potential Drug Target for Neurological Disorders

MCPH1, or microcephalin, is a protein that is expressed in the brain and is known for its role in the development and progression of various neurological disorders, including Alzheimer's disease. MCPH1 has also been shown to play a key role in the regulation of cell growth and differentiation, and is therefore considered a potential drug target (or biomarker).

MCPH1 is an approximately 120 amino acid long protein that was first discovered in 1997. It consists of two major domains: N-terminal 伪-helix and C-terminal 尾-coil. The N-terminal 伪-helix is 鈥嬧?媗ocated at the top of the protein and is an important structural domain that enables the protein to form an 伪-helical structure. The C-terminal 尾 coil is located at the bottom of the protein and is also an important structural domain that can enhance the stability of the protein.

In neurons, MCPH1 is mainly expressed in the cytoplasm, but is also evident in the nucleus. It interacts with tubulin (histone) and plays an important role in the growth and development of neurons. The interaction of MCPH1 with tubulin may explain why the expression level of MCPH1 in neurons is proportional to the content of tubulin.

In addition, MCPH1 is also related to neuronal apoptosis. Studies have shown that MCPH1 can inhibit neuronal apoptosis and play an important role in the process of neuronal death. These findings provide important clues for studying the role of MCPH1 in neuronal apoptosis.

MCPH1 also plays an important role in the growth and development of neurons. Studies have shown that MCPH1 can promote the growth and division of neuronal cells and play an important role in the process of neuronal differentiation. These findings provide important clues for studying the role of MCPH1 in neuronal growth and development.

MCPH1 is also associated with pain perception in neurons. Research shows that MCPH1 can promote pain perception in neurons and play an important role when neurons are stimulated. These findings provide important clues for studying the role of MCPH1 in neuronal pain perception.

In addition, MCPH1 has been shown to play an important role in many other physiological processes. For example, MCPH1 can promote immune system responses and plays an important role in cellular immune responses. In addition, MCPH1 is also related to neuronal memory and learning. Research shows that MCPH1 can affect the memory and learning of neurons and plays an important role in the learning and memory processes of neurons.

MCPH1 is a very important protein that plays an important role in the growth and development of neurons, pain perception and the immune system. These findings provide important clues for studying the role of MCPH1 and indicate that MCPH1 is a potential drug target (or biomarker). Future studies will further investigate the role of MCPH1 in neuronal function and explore the potential of MCPH1 as a drug target or biomarker.

Protein Name: Microcephalin 1

Functions: Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex

The "MCPH1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MCPH1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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MCPH1-AS1 | MCPH1-DT | MCRIP1 | MCRIP2 | MCRS1 | MCTP1 | MCTP2 | MCTS1 | MCTS2 | MCU | MCUB | MCUR1 | MDC1 | MDFI | MDFIC | MDGA1 | MDGA2 | MDH1 | MDH1B | MDH2 | MDK | MDM1 | MDM2 | MDM4 | MDN1 | MDS2 | ME1 | ME2 | ME3 | MEA1 | MEAF6 | MEAF6P1 | MEAK7 | Mechanoelectrical transducer (MET) channel | Mechanosensitive Ion Channel | MECOM | MECOM-AS1 | MeCP1 histone deacetylase (HDAC) complex | MECP2 | MECR | MED1 | MED10 | MED11 | MED12 | MED12L | MED13 | MED13L | MED14 | MED14P1 | MED15 | MED15P8 | MED16 | MED17 | MED18 | MED19 | MED20 | MED21 | MED22 | MED23 | MED24 | MED25 | MED26 | MED27 | MED28 | MED29 | MED30 | MED31 | MED4 | MED4-AS1 | MED6 | MED7 | MED8 | MED9 | MEDAG | Mediator Complex | Mediator of RNA Polymerase II Transcription | MEF2A | MEF2B | MEF2C | MEF2C-AS1 | MEF2C-AS2 | MEF2D | MEFV | MEG3 | MEG8 | MEG9 | MEGF10 | MEGF11 | MEGF6 | MEGF8 | MEGF9 | MEI1 | MEI4 | MEIG1 | MEIKIN | MEIOB | MEIOC | MEIOSIN | MEIS1 | MEIS1-AS2