CAMKMT Gene Involved in Neurotransmitter Synthesis and CNS Function

Target Name: CAMKMT

NCBI ID: G79823

CAMKMT

CAMKMT Gene Involved in Neurotransmitter Synthesis and CNS Function

CAMKMT (Calmodulin-lysine N-methyltransferase) is a gene that encodes a protein involved in the neurotransmitter synthesis and release process in the central nervous system (CNS). The CAMKMT gene has been implicated in the development and progression of various neurological disorders, including Alzheimer's disease, Parkinson's disease, and schizophrenia.

The neurotransmitter systems in the CNS are critical for the proper functioning of the brain, and the dysregulation of these systems has been implicated in the development of many neurological disorders. The neurotransmitter synthesis and release process is a critical step in this process, and the CAMKMT protein plays a crucial role in this process.

The CAMKMT gene is located on chromosome 11q22 and has been implicated in the development and progression of various neurological disorders. Studies have shown that individuals with certain genetic variations in the CAMKMT gene are at increased risk for developing these disorders. For example, individuals with the APTN3520T variant are at an increased risk of developing Alzheimer's disease, while individuals with the missenint variant are at an increased risk of developing Parkinson's disease.

In addition to its involvement in the neurotransmitter synthesis and release process, the CAMKMT protein has also been shown to play a role in the regulation of neurotransmitter signaling. The CAMKMT protein has been shown to interact with several neurotransmitter receptors, including dopamine, serotonin, and GABA. These interactions are important for the proper functioning of neurotransmitter signaling and are likely involved in the development and progression of various neurological disorders.

The CAMKMT gene has also been shown to be involved in the regulation of neurotransmitter synthesis and release in the peripheral nervous system (PNS). The PNS is responsible for the production and release of neurotransmitters, and the CAMKMT protein has been shown to play a role in this process.

In conclusion, the CAMKMT gene is involved in the neurotransmitter synthesis and release process in the CNS and has been implicated in the development and progression of various neurological disorders. The CAMKMT protein has also been shown to play a role in the regulation of neurotransmitter signaling and the regulation of neurotransmitter synthesis and release in the PNS. Further research is needed to fully understand the role of the CAMKMT gene in the development and progression of neurological disorders.

Protein Name: Calmodulin-lysine N-methyltransferase

Functions: Catalyzes the trimethylation of 'Lys-116' in calmodulin

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