Target Name: CARS2
NCBI ID: G79587
Review Report on CARS2 Target / Biomarker Content of Review Report on CARS2 Target / Biomarker
CARS2
Other Name(s): Cysteine tRNA ligase 2, mitochondrial (putative) | Probable cysteine--tRNA ligase, mitochondrial (isoform 1) | OTTHUMP00000018707 | FLJ12118 | translation initiation factor IF-2-like | cysteine tRNA ligase 2, mitochondrial (putative) | COXPD27 | CARS2 variant 1 | Cysteinyl-tRNA synthetase | Cysteine--tRNA ligase | SYCM_HUMAN | cysRS | cysteinyl-tRNA synthetase 2, mitochondrial | DKFZp667A2315 | cysteinyl-tRNA synthetase 2, mitochondrial (putative) | DKFZp686G08243 | FLJ42514 | Cysteinyl-tRNA synthetase 2, mitochondrial, transcript variant 1 | Probable cysteine--tRNA ligase, mitochondrial | Probable cysteinyl-tRNA synthetase, mitochondrial | CysRS

CARS2: A Mitochondrial Protein Regulating Protein Synthesis

CARS2, or Cysteine tRNA Ligase 2, is a protein that is expressed in the mitochondria. It plays a crucial role in the regulation of protein synthesis in the cell. CARS2 is a key enzyme in the process of translation, which is the process by which the information in mRNA is translated into protein.

CARS2 is a protein that is made up of 1,142 amino acids. It has a molecular weight of 189.1 kDa and a pI of 6.9. CARS2 is found in the cytoplasm of all cells and is also found in the mitochondria. It is a mitochondrial protein, which means that it is primarily found in the mitochondria, the powerhouses of the cell that provide energy for the cell's activities.

CARS2 is a critical enzyme that is involved in the regulation of protein synthesis in the cell. It is an essential enzyme for the translation of mRNAs into proteins. It does this by binding to specific regions of the mRNA and helping to remove tRNA from the ribosome . This process is called \"cleavage\" and it allows the ribosome to read the sequence of nucleotides in the mRNA and make the necessary changes to produce the corresponding protein.

CARS2 is also involved in the regulation of protein folding. It helps to ensure that the protein with the correct conformation can be correctly positioned to the receptor on the cell membrane after being synthesized from the nucleus, thereby achieving cell signaling.

CARS2 is a protein that has been shown to be a potential drug target. Studies have suggested that inhibiting the activity of CARS2 could be a useful therapy for a variety of diseases, including cancer, neurodegenerative diseases, and diseases that are caused by inflammation. This is because CARS2 is involved in the regulation of many important cellular processes, so any drug that inhibits its activity could have a broad range of potential applications.

In addition, CARS2 is also a potential biomarker for many diseases. Its expression is often reduced in diseases, such as cancer, neurodegenerative diseases, and diseases that are caused by inflammation. This could make it a useful indicator of the disease and could be used in the diagnosis and monitoring of these diseases.

CARS2 is also an attractive target for small molecules, peptides and antibodies because of its well-defined structure and its active site, which makes it easy to modulate. Additionally, CARS2 is a good scaffold for the development of new drugs, as the addition of small molecules to its active site can alter its activity and selectivity.

In conclusion, CARS2 is a protein that plays a crucial role in the regulation of protein synthesis in the cell. It is a key enzyme in the process of translation and is also involved in the regulation of protein folding. Its expression is often reduced in diseases and it is a potential drug target and biomarker. Therefore, the study of CARS2 and its potential applications in medicine and research is of great interest.

Protein Name: Cysteinyl-tRNA Synthetase 2, Mitochondrial

The "CARS2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CARS2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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