Target Name: CASC8
NCBI ID: G727677
Review Report on CASC8 Target / Biomarker Content of Review Report on CASC8 Target / Biomarker
CASC8
Other Name(s): cancer susceptibility 8 | CASC8 variant 2 | Cancer susceptibility 8, transcript variant 2 | Cancer susceptibility 8, transcript variant 1 | CARLo-1 | CARLO1 | LINC00860 | CASC8 variant 1

CASC8: Potential Drug Target for Cancer

Cancer Susceptibility 8 (CASC8) is a protein that is expressed in a variety of tissues throughout the body, including the breast, lung, and gastrointestinal tract. It is also a known protein that is associated with cancer, and research has suggested that it may play a role in the development and progression of certain types of cancer.

One of the main functions of CASC8 is its role in cell signaling. It is a member of the TGF-β (transforming growth factor beta) signaling pathway, which is a well-established pathway that plays a central role in the regulation of cell growth, differentiation, and survival. TGF-β signaling is involved in the development and maintenance of tissues and organs, including the immune system, and is a key factor in the development of many types of cancer.

CASC8 is also involved in the regulation of cell adhesion. Adhesion is the process by which cells stick together to form tissues and organs, and is a critical aspect of tissue development and repair. CASC8 is involved in the regulation of cell adhesion by promoting the stickiness of cells to their adhesion partners. This is important for the development and maintenance of tissues and organs, including the development of cancer.

In addition to its role in cell signaling and adhesion, CASC8 has also been suggested to be involved in the regulation of cell death. Cell death, also known as apoptosis, is an important aspect of normal tissue development and is regulated by a variety of factors, including the caspases, which are a group of proteins that play a key role in cell death. CASC8 is one of several proteins that have been shown to be involved in the regulation of caspase activity, which may be a potential drug target for cancer.

CASC8 is also expressed in a variety of tissues and is often used as a biomarker for cancer. For example, research has suggested that high levels of CASC8 may be associated with the development of certain types of cancer, such as breast cancer. This is because CASC8 has been shown to play a role in the regulation of cell growth and adhesion, which are important aspects of cancer development.

In addition to its potential role in cancer development, CASC8 has also been suggested to be involved in the regulation of cancer progression. For example, research has suggested that CASC8 may play a role in the regulation of the angiogenesis, which is the process by which new blood vessels are formed in tumors. This is important for the development and progression of cancer, as the growth of new blood vessels can provide a source of oxygen and nutrients for cancer cells.

CASC8 is also involved in the regulation of stem cell proliferation. Stem cells are a type of cell that have the ability to develop into any type of cell in the body, and they play a key role in the development and maintenance of tissues and organs. CASC8 is involved in the regulation of stem cell proliferation by promoting the growth and division of stem cells. This is important for the development and maintenance of tissues and organs, including the development of cancer.

In conclusion, CASC8 is a protein that is involved in a variety of physiological processes throughout the body. It is a member of the TGF-β signaling pathway and is involved in the regulation of cell signaling, adhesion, and cell death. It has also been suggested to be involved in the regulation of cancer development, progression, and stem cell proliferation. As a result, CASC8 may be a potential drug target or biomarker for cancer. Further research is needed to fully understand the role of CASC8 in cancer development and progression.

Protein Name: Cancer Susceptibility 8

The "CASC8 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CASC8 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

CASC9 | CASD1 | Casein Kinase | Casein kinase I | Casein Kinase I gamma | Casein kinase II (CKII) | CASK | CASKIN1 | CASKIN2 | CASKP1 | CASP1 | CASP10 | CASP12 | CASP14 | CASP16P | CASP1P2 | CASP2 | CASP3 | CASP4 | CASP4LP | CASP5 | CASP6 | CASP7 | CASP8 | CASP8AP2 | CASP9 | Caspase | CASQ1 | CASQ2 | CASR | CASS4 | CAST | CASTOR1 | CASTOR2 | CASTOR3P | CASZ1 | CAT | Cathepsin | CATIP | CATIP-AS1 | CATSPER1 | CATSPER2 | CATSPER2P1 | CATSPER3 | CATSPER4 | CATSPERB | CATSPERD | CATSPERE | CATSPERG | CATSPERZ | CAV1 | CAV2 | CAV3 | CAVIN1 | CAVIN2 | CAVIN3 | CAVIN4 | CBARP | CBFA2T2 | CBFA2T3 | CBFA2T3-ZNF651 corepressor complex | CBFB | CBL | CBLB | CBLC | CBLIF | CBLL1 | CBLL1P1 | CBLL2 | CBLN1 | CBLN2 | CBLN3 | CBLN4 | CBR1 | CBR1-AS1 | CBR3 | CBR3-AS1 | CBR4 | CBS | CBWD7 | CBX1 | CBX1P1 | CBX2 | CBX3 | CBX3P2 | CBX3P5 | CBX4 | CBX5 | CBX6 | CBX7 | CBX8 | CBY1 | CBY2 | CBY3 | CC2D1A | CC2D1B | CC2D2A | CC2D2B | CCAR1 | CCAR2