CASC3: A Protein Involved in Cellular Processes and Potential Drug Target

Target Name: CASC3

NCBI ID: G22794

CASC3

CASC3: A Protein Involved in Cellular Processes and Potential Drug Target

CASC3 (Mln 51) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the metal-尾-protein family and is composed of four distinct domains: a N- terminal transmembrane domain, a coiled-coil domain, a C-terminal T-cell receptor (TCR)伪-like domain, and a C-terminal N-terminal domain that contains a protein-coding region.

CASC3 is involved in the regulation of cellular processes that are critical for the development, growth, and survival of tissues. One of the most significant functions of CASC3 is its role in the regulation of inflammation.CASC3 has been shown to play a key role in the development of neuroinflammatory diseases, such as multiple sclerosis and rheumatoid arthritis.

CASC3 is also involved in the regulation of cell survival and metabolism. It has been shown to promote the survival of brain cells and to regulate the expression of genes that are involved in cell growth and differentiation.

CASC3 is also involved in the regulation of cellular signaling pathways. It has been shown to play a role in the regulation of T cell receptor (TCR) function, which is critical for the development and maintenance of the immune system.

In addition to its role in the regulation of cellular processes, CASC3 is also a potential drug target. Researchers have identified several potential drugs that can inhibit the activity of CASC3 and have shown that these drugs have the potential to treat a variety of diseases, including multiple sclerosis, rheumatoid arthritis, and neuroinflammatory diseases.

One of the most promising strategies for the treatment of CASC3-related diseases is the use of small molecules that can inhibit the activity of CASC3. Researchers have shown that a variety of small molecules, including inhibitors of protein-coding regions, can inhibit the activity of CASC3 and have the potential to treat CASC3-related diseases.

Another approach to the treatment of CASC3-related diseases is the use of antibodies that can target specific regions of CASC3. Researchers have shown that antibodies can be used to target specific regions of CASC3 and have the potential to treat CASC3-related diseases.

In conclusion, CASC3 is a protein that is involved in the regulation of a wide range of cellular processes that are critical for the development, growth, and survival of tissues. It is also involved in the regulation of inflammation, cell survival, and cellular signaling pathways.CASC3 is a potential drug target and has the potential to treat a variety of diseases, including multiple sclerosis, rheumatoid arthritis, and neuroinflammatory diseases. The use of small molecules and antibodies as potential treatments for CASC3-related diseases is an exciting area of research that has the potential to improve the health and well-being of many people.

Protein Name: CASC3 Exon Junction Complex Subunit

Functions: Required for pre-mRNA splicing as component of the spliceosome (PubMed:28502770, PubMed:29301961). Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs throughout all stages of mRNA metabolism thereby influencing downstream processes including nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD). Stimulates the ATPase and RNA-helicase activities of EIF4A3. Plays a role in the stress response by participating in cytoplasmic stress granules assembly and by favoring cell recovery following stress. Component of the dendritic ribonucleoprotein particles (RNPs) in hippocampal neurons. May play a role in mRNA transport. Binds spliced mRNA in sequence-independent manner, 20-24 nucleotides upstream of mRNA exon-exon junctions. Binds poly(G) and poly(U) RNA homomer

The "CASC3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CASC3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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