CAPZA2: A Potential Drug Target and Biomarker (G830)

Target Name: CAPZA2

NCBI ID: G830

CAPZA2

CAPZA2: A Potential Drug Target and Biomarker

The discovery of new drug targets and biomarkers is a critical aspect of modern medicine. Drug resistance, safety concerns, and the need for new treatments have led to an increased focus on developing small molecules and other compounds that can modulate biological pathways and disrupt disease processes. One promising candidate for drug targeting and biomarker is CAPZA2, a protein that has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative disorders, and inflammatory diseases.

CAPZA2: Structure and Function

CAPZA2 is a protein that belongs to the Z-catenin family, which is characterized by the presence of a Z-shaped transmembrane domain and a cytoplasmic tail. This protein is expressed in various tissues and organs, including the brain, pancreas, heart, and gastrointestinal tract, and is involved in various cellular processes, including cell adhesion, migration, and signaling.

One of the most significant features of CAPZA2 is its ability to interact with various signaling pathways, including TGF-β, NF-kappa-B, and PI3K/AKT. TGF-β is a well-known signaling pathway that plays a crucial role in cell growth, differentiation, and regulation, and is involved in the development of various diseases, including cancer. NF-kappa-B is a signaling pathway that regulates inflammation and immune responses, and is implicated in various diseases, including neurodegenerative disorders. PI3K/AKT is a signaling pathway that is involved in the regulation of cell survival and metabolism, and is implicated in various diseases, including cancer.

CAPZA2 has been shown to play a role in these signaling pathways, and its knockdown has been shown to reduce the effects of various signaling pathways, including TGF-β, NF-kappa-B, and PI3K/AKT. This suggests that CAPZA2 may be a potential drug target and biomarker for diseases that are characterized by the over-activation of these signaling pathways.

CAPZA2 as a Drug Target

The potential drug targeting of CAPZA2 is based on its involvement in various cellular processes that are involved in the development and progression of diseases. One of the primary targets of CAPZA2 is the regulation of cell adhesion, which is a critical process that is involved in the development of various tissues and organs. The over-activation of cell adhesion signaling pathways, including TGF-β, has been implicated in the development of various diseases, including cancer.

CAPZA2 has been shown to play a role in the regulation of cell adhesion, and its knockdown has been shown to reduce the effects of TGF-β signaling. This suggests that CAPZA2 may be a potential drug target for diseases that are characterized by the over-activation of TGF-β signaling pathways, including cancer.

Another potential drug target for CAPZA2 is its role in the regulation of neurodegenerative disorders. neurodegenerative disorders are a group of diseases that are characterized by the progressive loss of cognitive and motor function, and are often associated with the over-activation of signaling pathways, including TGF-β, NF-kappa-B, and PI3K/AKT. CAPZA2 has been shown to play a role in the regulation of neurodegenerative disorders, and its knockdown has been shown to reduce the effects of these signaling pathways.

CAPZA2 as a Biomarker

CAPZA2 has also been shown to be a potential biomarker for various diseases, including cancer, neurodegenerative disorders, and inflammatory diseases. The over-activation of signaling pathways, including TGF-β, NF-kappa-B, and PI3K/AKT, has

Protein Name: Capping Actin Protein Of Muscle Z-line Subunit Alpha 2

Functions: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments

The "CAPZA2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CAPZA2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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