ORAI2: Potential Drug Target Or Biomarker for Various Diseases

Target Name: ORAI2

NCBI ID: G80228

ORAI2

ORAI2: Potential Drug Target Or Biomarker for Various Diseases

ORAI2 (Open Reading Frame-Controlled Kallikrein-Inhibitors 2) is a protein that is expressed in various cell types of the human body, including blood cells, epithelial cells, and smooth muscle cells. It is a member of the kallikrein gene family, which is known for producing proteases that play a role in various cellular processes.

ORAI2 has been shown to have a variety of functions in the body, including the regulation of inflammation, cell signaling, and cell death. It is also known to be involved in the development and progression of various diseases, including cancer.

Recent studies have suggested that ORAI2 may be a drug target or biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. This is because ORAI2 has been shown to interact with a variety of different proteins, including T-cell receptor signaling pathways, which are involved in the development of many different diseases.

One of the potential benefits of targeting ORAI2 is that it has been shown to have a negative impact on the development and progression of cancer. Studies have shown that ORAI2 levels are elevated in various types of cancer, and that inhibiting ORAI2 may have a therapeutic benefit.

In addition to its potential as a cancer drug target, ORAI2 has also been suggested as a potential biomarker for the disease. The ORAI2 gene has been shown to be expressed in a variety of different tissues and cell types, including cancer cells, which suggests that it may be a useful marker for tracking disease progression.

ORAI2 is also involved in the regulation of cellular signaling pathways, which are important for the development and progression of many different diseases. For example, ORAI2 has been shown to be involved in the regulation of theNotch signaling pathway, which is involved in the development and progression of many different diseases, including cancer.

In addition to its role in cellular signaling pathways, ORAI2 is also involved in the regulation of inflammation. Studies have shown that ORAI2 levels are elevated in inflammatory tissues and that inhibiting ORAI2 may have a therapeutic benefit for the treatment of inflammatory disorders.

Overall, ORAI2 is a protein that has been shown to have a variety of functions in the body, including the regulation of inflammation, cell signaling, and cell death. Its potential as a drug target or biomarker makes it an attractive target for the development of new therapies for a variety of diseases.

Protein Name: ORAI Calcium Release-activated Calcium Modulator 2

Functions: Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)-selective current by synergy with the Ca(2+) sensor, STIM1

The "ORAI2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ORAI2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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