Target Name: BPIFB2
NCBI ID: G80341
Review Report on BPIFB2 Target / Biomarker Content of Review Report on BPIFB2 Target / Biomarker
BPIFB2
Other Name(s): BPIB2_HUMAN | BPI-like 1 | C20orf184 | Bactericidal/permeability-increasing protein-like 1 | Long palate, lung and nasal epithelium carcinoma associated 2 | Long palate, lung and nasal epithelium carcinoma-associated protein 2 | dJ726C3.2 | LPLUNC2 | OTTHUMP00000030612 | BPIL1 | RYSR | long palate, lung and nasal epithelium carcinoma-associated protein 2 | BPI fold containing family B member 2 | bactericidal/permeability-increasing protein-like 1 | BPI fold-containing family B member 2

BPIFB2: A Potential Cancer Target and Biomarker

BPIFB2 (BPIB2_HUMAN), a protein found in human placenta, has been identified as a potential drug target or biomarker in the field of cancer. Its unique structure and expression pattern have drawn the attention of researchers, who are trying to understand its role in the development and progression of cancer.

BPIFB2 is a transmembrane protein that is expressed in various tissues, including the placenta, brain, and heart. Its primary function is to regulate the intracellular signaling pathway known as the TGF-β pathway. This pathway is involved in cell growth, differentiation, and survival, and is a well-established target for many diseases, including cancer.

BPIFB2 plays a crucial role in the regulation of TGF-β signaling in the placenta. It has been shown to interact with several TGF-β signaling proteins, including SMAD2 and TGF-β1. This interaction is important for the regulation of placenta-specific gene expression, which is critical for the development and maintenance of the placenta.

BPIFB2 has also been shown to play a role in the regulation of cell survival and apoptosis. It has been shown to promote the survival of cancer cells, which may contribute to their resistance to chemotherapy and radiation.

BPIFB2 has also been shown to be involved in the regulation of cell migration and the development of cancer cell invasion. This may be important for the development of cancer stem cells, which are capable of self-renewal and have a role in the development of cancer.

BPIFB2 has also been shown to be involved in the regulation of the production of extracellular matrix (ECM) components, which are important for the development of cancer cells. ECM components include collagen, which is a protein that is involved in the structure and composition of the ECM, and ECM-derived growth factors, which are important for the growth and survival of cancer cells.

BPIFB2 has been shown to play a role in the regulation of the production of ECM-derived growth factors, which are important for the growth and survival of cancer cells. This may be important for the development of cancer cell invasion and metastasis.

BPIFB2 has also been shown to be involved in the regulation of the production of cell adhesion molecules, which are important for the maintenance of tissue structure and integrity. This may be important for the development of cancer cell invasion and metastasis.

BPIFB2 has also been shown to play a role in the regulation of the production of angiogenesis, which is the process by which new blood vessels are formed. This may be important for the development of cancer cell invasion and metastasis.

BPIFB2 has been shown to play a role in the regulation of the production of vascular endothelial growth factors (VEGF), which are important for the growth and survival of cancer cells. This may be important for the development of cancer cell invasion and metastasis.

BPIFB2 has also been shown to play a role in the regulation of the production of integrins, which are proteins that are involved in cell adhesion. This may be important for the development of cancer cell invasion and metastasis.

BPIFB2 has been shown to play a role in the regulation of the production of cell surface antigens, which are important for the development and maintenance of cancer cells. This may be important for the development of cancer cell invasion and metastasis.

BPIFB2 has also been shown to play a role in the regulation of the production of neurotrophic factors, which are important for the maintenance of nervous system function. This may be important for the development of cancer cell invasion and metastasis.

BPIFB2 has been shown to play a role in the regulation of the production of bone marrow-derived factors, which are important for the development and maintenance of

Protein Name: BPI Fold Containing Family B Member 2

The "BPIFB2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about BPIFB2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

BPIFB3 | BPIFB4 | BPIFB5P | BPIFB6 | BPIFC | BPNT1 | BPNT2 | BPTF | BPY2 | Bradykinin receptor | BRAF | BRAFP1 | Branched-chain alpha-ketoacid dehydrogenase (BCKD) complex | BRAP | BRAT1 | BRCA1 | BRCA1-A complex | BRCA1-BRCA2-containing complex | BRCA1P1 | BRCA2 | BRCC3 | BRD1 | BRD2 | BRD3 | BRD3OS | BRD4 | BRD7 | BRD7P3 | BRD8 | BRD9 | BRDT | BRF1 | BRF2 | BRI3 | BRI3BP | BRI3P1 | BRI3P2 | BRICD5 | BRINP1 | BRINP2 | BRINP3 | BRIP1 | BRISC complex | BRIX1 | BRK1 | BRME1 | BRMS1 | BRMS1L | Bromodomain adjacent to zinc finger domain protein | Bromodomain-containing protein | BROX | BRPF1 | BRPF3 | BRS3 | BRSK1 | BRSK2 | BRWD1 | BRWD1 intronic transcript 2 (non-protein coding) | BRWD1-AS2 | BRWD3 | BSCL2 | BSDC1 | BSG | BSN | BSN-DT | BSND | BSPH1 | BSPRY | BST1 | BST2 | BSX | BTAF1 | BTBD1 | BTBD10 | BTBD16 | BTBD17 | BTBD18 | BTBD19 | BTBD2 | BTBD3 | BTBD6 | BTBD7 | BTBD8 | BTBD9 | BTC | BTD | BTF3 | BTF3L4 | BTF3P11 | BTF3P7 | BTF3P9 | BTG1 | BTG2 | BTG2-DT | BTG3 | BTG4 | BTK | BTLA | BTN1A1 | BTN2A1