Target Name: BSG
NCBI ID: G682
Review Report on BSG Target / Biomarker Content of Review Report on BSG Target / Biomarker
BSG
Other Name(s): OK | EMPRIN | Extracellular matrix metalloproteinase inducer (EMMPRIN) | Basigin (isoform 1) | Hepatoma-associated antigen | Collagenase stimulatory factor | Extracellular matrix metalloproteinase inducer | extracellular matrix metalloproteinase inducer | leukocyte activation antigen M6 | SLC7A11 | hepatoma-associated antigen | Leukocyte activation antigen M6 | Basigin (CD147) | CD147 antigen | tumor cell-derived collagenase stimulatory factor | 5F7 | OK blood group antigen | M6 leukocyte activation antigen | BSG variant 1 | BASI_HUMAN | Basigin | Basigin isoform 3 | Basigin (Ok blood group), transcript variant 1 | Tumor cell-derived collagenase stimulatory factor (TCSF) | collagenase stimulatory factor | Basigin (isoform 2) | basigin (Ok blood group) | Tumor cell-derived collagenase stimulatory factor | CD147 | HAb18G | EMMPRIN | TCSF | M6 | Basigin (Ok blood group), transcript variant 2 | Basigin (Ok blood group), transcript variant 4 | BSG variant 2 | BSG variant 4

Understanding BISA: A Potential Drug Target for COPD, Asthma and Panic Disorder

Bronchodilator-induced spasm (BISA), also known as BSG, is a well-known reflex action that occurs in the human body. When a person breathes in deeply, their muscles constrict, and a feeling of coughing or tightness in the chest can occur . This reflex action is a natural response to the body's need for air, and it is usually not a cause for concern. However, in some cases, BISA can be a sign of an underlying medical condition.

BSG has been identified as a drug target and a potential biomarker for several diseases, including chronic obstructive pulmonary disease (COPD), asthma, and panic disorder. In this article, we will explore the science behind BISA and its potential as a drug target.

The Science Behind BISA

BISA is an reflex muscle contraction that occurs when a person breathes in deeply. It is a part of the body's natural response to the need for air. When a person inhales, their diaphragm expands and contracts, which sends a signal to the brain and the body to prepare for the incoming air.

The body's response to the deep breath is to constrict the muscles of the chest and neck, including the skeletal muscles, which are responsible for opening and closing the airways. This contraction causes the airways to narrow, which can lead to feelings of coughing or tightness in the chest.

BSG has been shown to play a role in several physiological processes in the body, including cardiovascular disease, respiratory disease, and neurological disorders.

Drug Targeting

BSG has been identified as a potential drug target for several diseases, including COPD, asthma, and panic disorder. Researchers are studying the effects of drugs that can modulate BSG activity on the molecular and cellular levels to treat these conditions.

In the treatment of COPD, bronchodilators are often used to alleviate symptoms of the disease. However, these medications can also increase the risk of BISA. Researchers are studying the effects of bronchodilators on BISA activity to determine if these medications can be used safely and effectively in reducing the risk of BISA.

In the treatment of asthma, corticosteroids are often used to alleviate symptoms of the disease. However, these medications can also increase the risk of BISA. Researchers are studying the effects of corticosteroids on BISA activity to determine if these medications can be used safely and effectively in reducing the risk of BISA.

In the treatment of panic disorder, antidepressants are often used to alleviate symptoms of the disease. However, these medications can also increase the risk of BISA. Researchers are studying the effects of antidepressants on BISA activity to determine if these medications can be used safely and effectively in reducing the risk of BISA.

Biomarker

BSG has also been identified as a potential biomarker for several diseases. By measuring the level of BISA activity in the body, researchers can gain insight into the underlying health of the patient.

For example, researchers have used BISA activity as a biomarker to diagnose COPD. By measuring the level of BISA activity in the body, researchers can determine if a patient has COPD. This could help doctors to accurately diagnose the severity of the disease and determine the most appropriate treatment.

Researchers have also used BISA activity as a biomarker to diagnose asthma. By measuring the level of BISA activity in the body, researchers can determine if a patient has asthma. This could help doctors to accurately diagnose the severity of the disease and determine the most appropriate treatment.

Conclusion

BSG is a well-known reflex action that occurs in the human body when a person breathes in deeply. In some cases, BISA can be a sign of an underlying medical condition. Researchers are studying the science behind BISA and its potential as a drug target for several diseases, including COPD, asthma, and panic disorder. By understanding the effects of BISA, doctors can develop more effective treatments for these conditions.

Protein Name: Basigin (Ok Blood Group)

Functions: Essential for normal retinal maturation and development (By similarity). Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors (PubMed:25957687). In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors (PubMed:25957687). May act as a potent stimulator of IL6 secretion in multiple cell lines that include monocytes (PubMed:21620857)

The "BSG Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about BSG comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

BSN | BSN-DT | BSND | BSPH1 | BSPRY | BST1 | BST2 | BSX | BTAF1 | BTBD1 | BTBD10 | BTBD16 | BTBD17 | BTBD18 | BTBD19 | BTBD2 | BTBD3 | BTBD6 | BTBD7 | BTBD8 | BTBD9 | BTC | BTD | BTF3 | BTF3L4 | BTF3P11 | BTF3P7 | BTF3P9 | BTG1 | BTG2 | BTG2-DT | BTG3 | BTG4 | BTK | BTLA | BTN1A1 | BTN2A1 | BTN2A2 | BTN2A3P | BTN3A1 | BTN3A2 | BTN3A3 | BTNL10P | BTNL2 | BTNL3 | BTNL8 | BTNL9 | BTRC | BUB1 | BUB1B | BUB1B-PAK6 | BUB3 | BUD13 | BUD23 | BUD31 | Butyrophilin | Butyrophilin subfamily 3 member A (BTN3A) | BVES | BVES-AS1 | BYSL | BZW1 | BZW1-AS1 | BZW1P2 | BZW2 | C-C chemokine receptor | C10orf105 | C10orf113 | C10orf120 | C10orf126 | C10orf143 | C10orf53 | C10orf55 | C10orf62 | C10orf67 | C10orf71 | C10orf71-AS1 | C10orf82 | C10orf88 | C10orf88B | C10orf90 | C10orf95 | C10orf95-AS1 | C11orf16 | C11orf21 | C11orf24 | C11orf40 | C11orf42 | C11orf52 | C11orf54 | C11orf58 | C11orf65 | C11orf68 | C11orf71 | C11orf80 | C11orf86 | C11orf87 | C11orf91 | C11orf96 | C11orf97 | C11orf98