BRD7: Role in Cell Signaling and Development (G29117)

Target Name: BRD7

NCBI ID: G29117

BRD7

BRD7: Role in Cell Signaling and Development

BRD7 (SMARCI1) is a protein that is expressed in various tissues throughout the body, including the brain, lungs, heart, and gastrointestinal tract. It is a member of the SMARTCAN gene family, which is characterized by the presence of a specific transcription factor Binding region (T-cell factor-responsive element) in its amino acid sequence.

BRD7 is known for its role in cell signaling and development. It has been shown to play a role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the key functions of BRD7 is its ability to interact with other proteins, particularly those that are involved in cell signaling pathways. This interaction is important for the regulation of cellular processes such as cell growth, apoptosis (programmed cell death), and inflammation.

BRD7 has also been shown to play a role in the regulation of gene expression. It has been shown to interact with factors such as p53, which is a well-known tumor suppressor gene that is involved in the regulation of cellular processes such as cell growth , apoptosis, and DNA repair.

BRD7 is also involved in the regulation of cellular transport processes. It has been shown to interact with proteins such as the transmembrane protein known as TAL1, which is involved in the regulation of cell signaling pathways.

In addition to its role in cell signaling and development, BRD7 has also been shown to play a role in the regulation of cellular processes such as cell adhesion and migration. It has been shown to interact with proteins such as E-cadherin, which is a transmembrane protein that is involved in cell signaling pathways and has been shown to play a role in the regulation of cell adhesion.

BRD7 has also been shown to play a role in the regulation of cellular processes such as cell cycle progression and apoptosis. It has been shown to interact with proteins such as the cyclin D1 protein, which is involved in the regulation of cell cycle progression and has been shown to play a role in the regulation of apoptosis.

In addition to its role in cell signaling and development, BRD7 has also been shown to play a role in the regulation of cellular processes such as cell adhesion and migration. It has been shown to interact with proteins such as E-cadherin, which is a transmembrane protein that is involved in cell signaling pathways and has been shown to play a role in the regulation of cell adhesion.

BRD7 has also been shown to play a role in the regulation of cellular processes such as cell cycle progression and apoptosis. It has been shown to interact with proteins such as the cyclin D1 protein, which is involved in the regulation of cell cycle progression and has been shown to play a role in the regulation of apoptosis.

In addition to its role in cell signaling and development, BRD7 has also been shown to play a role in the regulation of cellular processes such as cell adhesion and migration. It has been shown to interact with proteins such as E-cadherin, which is a transmembrane protein that is involved in cell signaling pathways and has been shown to play a role in the regulation of cell adhesion.

BRD7 has also been shown to play a role in the regulation of cellular processes such as cell cycle progression and apoptosis. It has been shown to interact with proteins such as the cyclin D1 protein, which is involved in the regulation of cell cycle progression and has been shown to play a role in the regulation of apoptosis.

In addition to its role in cell signaling and development, BRD7 has also been shown to play a role in the regulation of cellular processes such as

Protein Name: Bromodomain Containing 7

Functions: Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at 'Tyr-216'. Down-regulates TRIM24-mediated activation of transcriptional activation by AR (By similarity). Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at 'Lys-9' (H3K9ac). Binds to the ESR1 promoter. Recruits BRCA1 and POU2F1 to the ESR1 promoter. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activation. Promotes acetylation of TP53 at 'Lys-382', and thereby promotes efficient recruitment of TP53 to target promoters. Inhibits cell cycle progression from G1 to S phase

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•   general information;
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•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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