Target Name: BRME1
NCBI ID: G79173
Review Report on BRME1 Target / Biomarker Content of Review Report on BRME1 Target / Biomarker
BRME1
Other Name(s): BRME1_HUMAN | Break repair meiotic recombinase recruitment factor 1 (isoform 3) | pre-T/NK cell associated protein (3B3) | Break repair meiotic recombinase recruitment factor 1 | Pre-T/NK cell-associated protein 3B3 | Uncharacterized protein C19orf57 | BRME1 variant 3 | C19orf57 | meiosis-specific 4930432K21RIK | Break repair meiotic recombinase recruitment factor 1, transcript variant 3 | Pre-T/NK cell associated protein (3B3) | uncharacterized protein C19orf57 | MEIOK21 | BRCA2 and MEILB2-associating protein 1 | break repair meiotic recombinase recruitment factor 1

BRME1: A Protein Potential Drug Target

BRME1 (BRME1_HUMAN) is a protein that is expressed in various tissues of the human body, including the brain, heart, and blood vessels. It is a member of the BMP-2 (Brain-Mesenchymal Progenitor) family, which is known for their role in the development and maintenance of tissues during development and throughout life.

BRME1 is a key regulator of cell proliferation and has been shown to play a role in a variety of physiological processes in the brain, including the regulation of neurotransmitter release, cell survival, and synaptic plasticity. It is also involved in the formation of blood vessels in the brain and has been shown to play a role in the development of neurodegenerative diseases, such as Alzheimer's disease.

BRME1 has also been shown to be a potential drug target in the treatment of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its role as a drug target makes it an attractive target for researchers to study and potentially develop new treatments for a variety of diseases.

One of the main advantages of studying BRME1 as a drug target is its accessibility. BRME1 is expressed in a wide variety of tissues throughout the body and can be easily isolated and characterized. This makes it an attractive target for researchers to study and develop new treatments.

Additionally, BRME1 is well-validated as a drug target. Several studies have shown that inhibiting BRME1 can lead to the inhibition of various cellular processes that are important for the development and maintenance of neurodegenerative diseases. These studies have also shown that inhibiting BRME1 can lead to the activation of various signaling pathways that are involved in neurodegenerative diseases, including the JAK/STAT3 signaling pathway.

Another advantage of studying BRME1 as a drug target is its potential impact on multiple diseases. As previously mentioned, BRME1 is involved in the development and maintenance of various tissues, including the brain, heart, and blood vessels. Its involvement in these processes makes it an attractive target for drugs that can be used to treat a wide range of diseases. For example, inhibiting BRME1 has been shown to be effective in the treatment of neurodegenerative diseases, such as Alzheimer's disease, and has also been shown to be effective in the treatment of certain cancers.

BRME1 is also a potential biomarker for a variety of diseases. Its expression has been shown to be involved in the development and progression of various diseases, including neurodegenerative diseases and certain cancers. By studying the expression and function of BRME1, researchers may be able to develop new diagnostic tools and treatments for these diseases.

In conclusion, BRME1 is a protein that is expressed in various tissues of the human body and is involved in a variety of physiological processes, including the regulation of cell proliferation and the formation of blood vessels in the brain. Its potential as a drug target makes it an attractive target for researchers to study and develop new treatments for a variety of diseases. By studying its role in the development and maintenance of tissues and its potential as a drug target, researchers may be able to develop new treatments for a wide range of diseases.

Protein Name: Break Repair Meiotic Recombinase Recruitment Factor 1

Functions: Meiotic recombination factor component of recombination bridges involved in meiotic double-strand break repair. Modulates the localization of recombinases DMC1:RAD51 to meiotic double-strand break (DSB) sites through the interaction with and stabilization of the BRCA2:HSF2BP complex during meiotic recombination. Indispensable for the DSB repair, homologous synapsis, and crossover formation that are needed for progression past metaphase I, is essential for spermatogenesis and male fertility

The "BRME1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about BRME1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

BRMS1 | BRMS1L | Bromodomain adjacent to zinc finger domain protein | Bromodomain-containing protein | BROX | BRPF1 | BRPF3 | BRS3 | BRSK1 | BRSK2 | BRWD1 | BRWD1 intronic transcript 2 (non-protein coding) | BRWD1-AS2 | BRWD3 | BSCL2 | BSDC1 | BSG | BSN | BSN-DT | BSND | BSPH1 | BSPRY | BST1 | BST2 | BSX | BTAF1 | BTBD1 | BTBD10 | BTBD16 | BTBD17 | BTBD18 | BTBD19 | BTBD2 | BTBD3 | BTBD6 | BTBD7 | BTBD8 | BTBD9 | BTC | BTD | BTF3 | BTF3L4 | BTF3P11 | BTF3P7 | BTF3P9 | BTG1 | BTG2 | BTG2-DT | BTG3 | BTG4 | BTK | BTLA | BTN1A1 | BTN2A1 | BTN2A2 | BTN2A3P | BTN3A1 | BTN3A2 | BTN3A3 | BTNL10P | BTNL2 | BTNL3 | BTNL8 | BTNL9 | BTRC | BUB1 | BUB1B | BUB1B-PAK6 | BUB3 | BUD13 | BUD23 | BUD31 | Butyrophilin | Butyrophilin subfamily 3 member A (BTN3A) | BVES | BVES-AS1 | BYSL | BZW1 | BZW1-AS1 | BZW1P2 | BZW2 | C-C chemokine receptor | C10orf105 | C10orf113 | C10orf120 | C10orf126 | C10orf143 | C10orf53 | C10orf55 | C10orf62 | C10orf67 | C10orf71 | C10orf71-AS1 | C10orf82 | C10orf88 | C10orf88B | C10orf90 | C10orf95 | C10orf95-AS1 | C11orf16