Target Name: AMN
NCBI ID: G81693
Review Report on AMN Target / Biomarker Content of Review Report on AMN Target / Biomarker
AMN
Other Name(s): Amnion associated transmembrane protein | amnion associated transmembrane protein | visceral endoderm-specific type 1 transmembrane protein | AMNLS_HUMAN | amnionless | Protein amnionless | PRO1028 | amnionless homolog | Visceral endoderm-specific type 1 transmembrane protein | Soluble protein amnionless | IGS2

AMN: The Potential Drug Target and Biomarker for Amnion Associated Transmembrane Protein

Amnion Associated Transmembrane Protein (AMN) is a protein that is expressed in various tissues of the body, including the placenta, uterus, and fetal brain. It is a member of the transmembrane protein family, which means that it spans the cell membrane and interacts with various intracellular and extracellular molecules. The function of AMN is not well understood, but it is involved in several physiological processes, including fetal development, angiogenesis, and tissue repair.

AMN has also been implicated in several diseases, including preterm birth, low birth weight, and placental abruption. It is thought to play a crucial role in these conditions, as it may help to regulate the formation and function of the placenta, which is responsible for providing oxygen and nutrients to the developing fetus.

Despite the significant research on AMN, the exact function of this protein and its potential as a drug target or biomarker remains unclear. In this article, we will explore the potential role of AMN in disease, as well as its potential as a drug target.

The Role of AMN in Disease

AMN has been implicated in several diseases, including preterm birth, low birth weight, and placental abruption. Preterm birth is a condition in which a baby is born before 37 weeks of gestation. It is a leading cause of infant mortality and is a significant public health issue.

AMN has been shown to be involved in the development and function of the placenta, which is responsible for providing oxygen and nutrients to the developing fetus. It is thought to play a crucial role in regulating the formation and function of the placenta, as well as the production of certain hormones that are important for fetal growth and development.

In addition to its role in fetal development, AMN has also been implicated in the regulation of inflammation. It is a known regulator of pro-inflammatory cytokines, which are important for the immune response and tissue repair.

The potential drug target for AMN is its role in the regulation of inflammation and fetal development. Researchers are interested in developing drugs that can modulate the activity of AMN and improve outcomes in individuals with preterm birth and other conditions that are associated with inflammation.

Potential Biomarkers for AMN

AMN is a protein that is expressed in various tissues of the body, including the placenta, uterus, and fetal brain. It is a member of the transmembrane protein family, which means that it spans the cell membrane and interacts with various intracellular and extracellular molecules.

Because AMN is involved in several physiological processes, it is a potential biomarker for several diseases. For example, it has been shown to be involved in the regulation of fetal development, angiogenesis, and tissue repair. It is also thought to play a role in the regulation of inflammation, which is a significant contributor to several diseases, including preterm birth and low birth weight.

Research on AMN as a biomarker for disease has shown that it may be a valuable tool for the diagnosis and treatment of these conditions. For example, by measuring the levels of AMN in tissue samples from individuals with preterm birth, researchers have been able to identify potential biomarkers for this condition. They have also used these biomarkers to develop new treatments for preterm birth and other conditions associated with inflammation.

Conclusion

In conclusion, AMN is a protein that is involved in several physiological processes and has been implicated in the development and function of the placenta, as well as the regulation of inflammation. Its potential as a drug target or biomarker for several diseases, including preterm birth and low birth weight, makes it an important area of research for scientists and clinicians. Further studies are needed to fully understand the role of AMN in disease and its potential as a drug target or biomarker.

Protein Name: Amnion Associated Transmembrane Protein

Functions: Membrane-bound component of the endocytic receptor formed by AMN and CUBN (PubMed:14576052, PubMed:30523278, PubMed:29402915). Required for normal CUBN glycosylation and trafficking to the cell surface (PubMed:14576052, PubMed:29402915). The complex formed by AMN and CUBN is required for efficient absorption of vitamin B12 (PubMed:12590260, PubMed:14576052, PubMed:26040326). Required for normal CUBN-mediated protein transport in the kidney (Probable)

The "AMN Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about AMN comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

AMN1 | AMOT | AMOTL1 | AMOTL2 | AMP Deaminase | AMP-activated protein kinase (AMPK) | AMP-activated protein kinase alpha1beta1gamma1 | AMP-activated protein kinase alpha2beta1gamma1 | AMP-activated protein kinase alpha2beta1gamma2 | AMP-activated protein kinase alpha2beta2gamma2 | AMPD1 | AMPD2 | AMPD3 | AMPH | AMT | AMTN | AMY1A | AMY1B | AMY1C | AMY2A | AMY2B | Amylin receptor | Amyloid beta A4 precursor protein-binding family (APP-BP) | AMZ1 | AMZ2 | AMZ2P1 | Anandamide membrane transporter (AMT) | ANAPC1 | ANAPC10 | ANAPC10P1 | ANAPC11 | ANAPC13 | ANAPC15 | ANAPC16 | ANAPC1P1 | ANAPC1P2 | ANAPC2 | ANAPC4 | ANAPC5 | ANAPC7 | ANG | ANGEL1 | ANGEL2 | Angiogenic Factor | Angiotensin receptor (AT) | ANGPT1 | ANGPT2 | ANGPT4 | ANGPTL1 | ANGPTL2 | ANGPTL3 | ANGPTL4 | ANGPTL5 | ANGPTL6 | ANGPTL7 | ANGPTL8 | ANHX | ANK1 | ANK2 | ANK3 | ANKAR | ANKDD1A | ANKDD1B | ANKEF1 | ANKFN1 | ANKFY1 | ANKH | ANKHD1 | ANKHD1-EIF4EBP3 | ANKIB1 | ANKK1 | ANKLE1 | ANKLE2 | ANKMY1 | ANKMY2 | ANKRA2 | ANKRD1 | ANKRD10 | ANKRD11 | ANKRD12 | ANKRD13A | ANKRD13B | ANKRD13C | ANKRD13D | ANKRD16 | ANKRD17 | ANKRD18A | ANKRD18B | ANKRD18CP | ANKRD18DP | ANKRD19P | ANKRD2 | ANKRD20A1 | ANKRD20A11P | ANKRD20A12P | ANKRD20A13P | ANKRD20A17P | ANKRD20A18P | ANKRD20A19P | ANKRD20A2P