Target Name: PARD6G
NCBI ID: G84552
Review Report on PARD6G Target / Biomarker Content of Review Report on PARD6G Target / Biomarker
PARD6G
Other Name(s): FLJ45701 | PAR-6 gamma | PAR-6G | Par-6 family cell polarity regulator gamma | Partitioning-defective protein 6 homolog gamma | PAR6G | PAR6gamma | par-6 family cell polarity regulator gamma | Partitioning defective 6 homolog gamma | OTTHUMP00000163844 | PAR-6 gamma protein | PAR6G_HUMAN | PAR6D | par-6 partitioning defective 6 homolog gamma

PARD6G: A Potential Drug Target and Biomarker

Pard6g, also known as FLJ45701, is a protein that is expressed in various tissues of the human body, including the brain, heart, and liver. Its function is not well understood, but it is known to play a role in the regulation of cell proliferation and survival. Several studies have suggested that Pard6g may have potential as a drug target or biomarker.

The protein Pard6g is a member of the Pard family of proteins, which are known to play a role in the regulation of cell growth and differentiation. Pard6g is similar to other proteins in the Pard family, such as Pardin and Pardroptidin, which are also known to be involved in the regulation of cell proliferation and survival.

One of the key functions of Pard6g is its role in the regulation of cell proliferation. Several studies have shown that Pard6g plays a negative role in the regulation of cell proliferation by inhibiting the activity of the oncogene transforming growth factor beta (TGF-β). TGF-β is a well-known protein that is involved in the regulation of cell growth, including cell proliferation.

In addition to its role in cell proliferation, Pard6g has also been shown to play a role in the regulation of cell survival. Several studies have shown that Pard6g plays a negative role in the regulation of cell survival by inhibiting the activity of the neurotrophic factor PDGF. PDGF is a protein that is involved in the regulation of cell survival, including the survival of brain cells.

The potential drug target status of Pard6g is further supported by its expression in various tissues of the human body, including the brain. The brain is a particularly sensitive to changes in cell proliferation and survival, making it an attractive target for drugs that are designed to inhibit the activity of Pard6g.

In conclusion, Pard6g is a protein that is known to play a role in the regulation of cell proliferation and survival. Its potential as a drug target or biomarker makes it an attractive target for future studies. Further research is needed to fully understand the function of Pard6g and its potential as a drug.

Protein Name: Par-6 Family Cell Polarity Regulator Gamma

Functions: Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (By similarity)

The "PARD6G Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PARD6G comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PARD6G-AS1 | PARG | PARGP1 | PARK7 | PARL | PARM1 | PARM1-AS1 | PARN | PARP1 | PARP10 | PARP11 | PARP12 | PARP14 | PARP15 | PARP16 | PARP2 | PARP3 | PARP4 | PARP6 | PARP8 | PARP9 | PARPBP | PARS2 | PART1 | PARTICL | PARVA | PARVB | PARVG | Parvovirus initiator complex | PASD1 | PASK | Patatin-like phospholipase domain-containing protein | PATE1 | PATE2 | PATE3 | PATE4 | PATJ | PATL1 | PATL2 | PATZ1 | PAUPAR | PAWR | PAX1 | PAX2 | PAX3 | PAX4 | PAX5 | PAX6 | PAX6-AS1 | PAX7 | PAX8 | PAX8-AS1 | PAX9 | PAXBP1 | PAXBP1-AS1 | PAXIP1 | PAXIP1-AS2 | PAXIP1-DT | PAXX | PBDC1 | PBK | PBLD | PBOV1 | PBRM1 | PBX1 | PBX2 | PBX3 | PBX3-DT | PBX4 | PBXIP1 | PC | PCA3 | PCAF complex | PCARE | PCAT1 | PCAT14 | PCAT18 | PCAT19 | PCAT2 | PCAT29 | PCAT4 | PCAT5 | PCAT6 | PCAT7 | PCBD1 | PCBD2 | PCBP1 | PCBP1-AS1 | PCBP2 | PCBP2-OT1 | PCBP2P2 | PCBP3 | PCBP3-AS1 | PCBP4 | PCCA | PCCA-DT | PCCB | PCDH1 | PCDH10 | PCDH11X