Target Name: TNFRSF18
NCBI ID: G8784
Review Report on TNFRSF18 Target / Biomarker Content of Review Report on TNFRSF18 Target / Biomarker
TNFRSF18
Other Name(s): TNFRSF18 variant 2 | TNR18_HUMAN | activation-inducible TNFR family receptor | GITR-D | Tumor necrosis factor receptor superfamily member 18 (isoform 1) | TNF receptor superfamily activation-inducible protein | TNF receptor superfamily member 18, transcript variant 1 | CD357 | TNF receptor superfamily member 18, transcript variant 2 | TNF receptor superfamily member 18 | TNFRSF18 variant 1 | Glucocorticoid-induced TNFR-related protein | Tumor necrosis factor receptor superfamily member 18 | GITR | glucocorticoid-induced TNFR-related protein | Activation-inducible TNFR family receptor | Tumor necrosis factor receptor superfamily member 18 (isoform 2) | ENERGEN | AITR

Understanding TNFRSF18: Potential Drug Targets and Biomarker for Diseases

TNFRSF18 (TNFRSF18 variant 2) is a protein that is expressed in various tissues throughout the body. It is a member of the TNF receptor family, which is a group of cytokines that play a crucial role in cellular signaling. TNFRSF18 is involved in several physiological processes in the body, including inflammation, immune response, and metabolism.

Despite its importance, TNFRSF18 has remained a relatively unstudied protein. There are only a few studies that have investigated its role in various biological processes, and most of these studies have focused on its functions in diseases such as cancer and neurodegenerative diseases.

However, recent research has shed new light on the potential drug targets of TNFRSF18. Several studies have identified potential drug targets for this protein, which may have implications for the treatment of a variety of diseases.

One of the potential drug targets for TNFRSF18 is its role in inflammation. TNFRSF18 is involved in the regulation of inflammatory responses, and it has been shown to play a key role in the regulation of tissue inflammation. Several studies have suggested that inhibiting the activity of TNFRSF18 may be a promising approach for the treatment of inflammatory diseases such as rheumatoid arthritis and inflammatory bowel disease.

Another potential drug target for TNFRSF18 is its role in cell signaling. TNFRSF18 is involved in the regulation of cellular signaling pathways, and several studies have suggested that it may be a useful target for the treatment of diseases that are characterized by abnormal cellular signaling. For example, TNFRSF18 has been shown to play a key role in the regulation of stem cell proliferation, and abnormal stem cell proliferation has been linked to the development of several diseases, including cancer.

In addition to its potential drug targets, TNFRSF18 has also been identified as a potential biomarker for several diseases. The ability of TNFRSF18 to be expressed in various tissues and its involvement in several physiological processes make it an attractive candidate for use as a biomarker for a variety of diseases. Several studies have shown that the expression of TNFRSF18 is associated with the development of several diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

Overall, the study of TNFRSF18 is an exciting area of research with potential implications for the treatment of a variety of diseases. While more research is needed to fully understand the functions of this protein and its potential drug targets, the study of TNFRSF18 is a promising direction for future research in the field of molecular biology and pharmacology.

Protein Name: TNF Receptor Superfamily Member 18

Functions: Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway

The "TNFRSF18 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about TNFRSF18 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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