FGF21: A Protein Critical for Tissue Development and Maintenance

Target Name: FGF21

NCBI ID: G26291

FGF21

Other Name(s): FGF21_HUMAN | FGF-21 | Fibroblast growth factor 21 | fibroblast growth factor 21 | FGF19X

FGF21: A Protein Critical for Tissue Development and Maintenance

FGF21 (FGF21_HUMAN), also known as FGF-21, is a protein that is expressed in various tissues throughout the body, including the skin, hair, nails, and bones. It is a member of the FGF family, which is known for their role in tissue growth and development. FGF21 is a critical factor in the development and maintenance of tissues, including organs, throughout the lifespan.

FGF21 is a transmembrane protein that is expressed in the skin, hair, nails, and bones. It is a type of cytoskeletal protein that is involved in the regulation of cell signaling pathways. FGF21 plays a vital role in the development and maintenance of tissues, including organs, throughout the lifespan.

One of the key functions of FGF21 is its role in the regulation of cell proliferation. FGF21 is a potent growth factor that can stimulate the growth and expansion of various types of cells, including epithelial, muscle, and neural cells. It is also involved in the regulation of cell differentiation, and has been shown to play a role in the development and maintenance of tissues such as the skin, hair, and nails.

Another important function of FGF21 is its role in the regulation of cell migration. FGF21 is involved in the regulation of cell adhesion and can promote the movement of cells along the body's surface. This is important for the development and maintenance of tissues such as tissues that are in contact with the body's surface, such as the skin and the lining of the body's various chambers.

FGF21 is also involved in the regulation of cellular signaling pathways. It is a potent receptor for various signaling molecules, including TGF-β1 and PDGF. TGF-β1 and PDGF are important growth factors that play a critical role in the development and maintenance of tissues . FGF21 has been shown to play a role in the regulation of TGF-β1 and PDGF signaling pathways, and is involved in the regulation of cell proliferation and differentiation.

FGF21 is also involved in the regulation of the production of extracellular matrix (ECM) components. ECM is a complex mixture of proteins that is involved in the structure and function of tissues. FGF21 is involved in the production of ECM components, including collagen and elastin. , which are important for the structure and function of tissues.

FGF21 is also involved in the regulation of cellular signaling pathways that are involved in the development and maintenance of tissues. FGF21 plays a critical role in the regulation of the Wnt signaling pathway, which is involved in the development and maintenance of tissues that are involved in vision and hearing. FGF21 is also involved in the regulation of the Notch signaling pathway, which is involved in the development and maintenance of tissues that play a critical role in the development and maintenance of tissues.

In conclusion, FGF21 is a critical protein that is involved in the development and maintenance of tissues throughout the lifespan. It is a potent growth factor that can stimulate the growth and expansion of various types of cells, and is involved in the regulation of cell proliferation , migration, and signaling pathways. FGF21 is also involved in the regulation of the production of ECM components and the development and maintenance of tissues. Given its role in the development and maintenance of tissues, FGF21 is a potential drug target or biomarker that could be targeted by therapeutic agents for the treatment of various diseases.

Protein Name: Fibroblast Growth Factor 21

Functions: Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. Regulates systemic glucose homeostasis and insulin sensitivity

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
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•   related combination drugs;
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