FGFBP3: Potential Drug Target for Tissue Growth and Development

Target Name: FGFBP3

NCBI ID: G143282

FGFBP3

FGFBP3: Potential Drug Target for Tissue Growth and Development

Fibroblast growth factor-binding protein 3 (FGFBP3) is a protein that is expressed in various tissues throughout the body, including the skin, hair, nails, and bones. It is a member of the FGF family of proteins, which are known for their role in cell proliferation and growth. FGFBP3 has been shown to play a role in the regulation of cellular processes that are important for tissue growth and development, and it is potential drug target for various diseases.

The FGF family of proteins is characterized by the presence of a specific domain called the FGF-binding domain (FBD), which is responsible for the protein's ability to interact with the FGF receptor. The FBD is a transmembrane protein that is involved in the regulation of cell proliferation, differentiation, and survival. It is composed of multiple domains, including an extracellular domain that is involved in cell adhesion and interactions with other proteins, a transmembrane domain that spans the cell membrane, and an intracellular domain that interacts with various intracellular signaling pathways.

FGFBP3 is a 14 kDa protein that is expressed in various tissues, including the skin, hair, nails, and bones. It is a type of FGFBP protein, which is characterized by the presence of the FGF-binding domain. FGFBP3 is involved in the regulation of cellular processes that are important for tissue growth and development, such as cell proliferation, differentiation, and survival.

One of the key functions of FGFBP3 is its role in the regulation of cell proliferation. FGFBP3 has been shown to play a negative role in the regulation of cell proliferation by the FGF signaling pathway. This is achieved by the FGFBP3 protein binding to the FGF receptor and inhibiting the FGF signaling pathway. This mechanism of action is important for the regulation of normal tissue growth and development, as well as the treatment of various diseases such as cancer.

FGFBP3 is also involved in the regulation of cell differentiation and tissue homeostasis. This is achieved by the FGFBP3 protein binding to various intracellular signaling pathways, including the TGF-β signaling pathway. TGF-β is a cytokine that plays a key role in the regulation of cell proliferation, differentiation, and survival. FGFBP3 has been shown to play a negative role in the regulation of TGF-β signaling pathway, which is important for the regulation of normal tissue growth and development.

FGFBP3 is also involved in the regulation of cell survival. This is achieved by the FGFBP3 protein binding to various intracellular signaling pathways, including the PDGF signaling pathway. PDGF is a cytokine that plays a key role in the regulation of cell survival and proliferation. FGFBP3 has been shown to play a positive role in the regulation of PDGF signaling pathway, which is important for the regulation of normal tissue growth and development.

In addition to its role in the regulation of cell proliferation, differentiation, and survival, FGFBP3 is also involved in the regulation of cellular interactions and tissue architecture. This is achieved by the FGFBP3 protein binding to various intracellular signaling pathways, including the Wnt signaling pathway. Wnt is a cytokine that plays a key role in the regulation of cell-cell interactions and tissue architecture. FGFBP3 has been shown to play a positive role in the regulation of Wnt signaling pathway, which is important for the regulation of normal tissue growth and development.

FGFBP3 is also involved in the regulation of cellular signaling pathways that are important for the regulation of pain perception and neurotransmission. This is achieved by the FGFBP3 protein binding to various intracellular signaling pathways, including the TrkA signaling pathway. TrkA is a G protein-coupled receptor that is involved in the regulation of pain perception and neurotransmission. FGFBP3 has been shown to play a negative role in the regulation of TrkA signaling pathway, which is important for the regulation of

Protein Name: Fibroblast Growth Factor Binding Protein 3

Functions: Heparin-binding protein which binds to FGF2, prevents binding of FGF2 to heparin and probably inhibits immobilization of FGF2 on extracellular matrix glycosaminoglycans, allowing its release and subsequent activation of FGFR signaling which leads to increased vascular permeability

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
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