FGF-7: Key Regulator of Tissue Development and Disease (G2252)

Target Name: FGF7

NCBI ID: G2252

FGF7

FGF-7: Key Regulator of Tissue Development and Disease

Fibroblast growth factor-7 (FGF-7), also known as HBGF-7, is a protein that plays a crucial role in the development and maintenance of tissues, including muscles, bones, and skin. It is a transmembrane glycoprotein that belongs to the FGF family, which also includes the well-known proteins FGF-1, FGF-2, and FGF-3.

FGF-7 is a key regulator of cell proliferation and differentiation, as well as a regulator of cell-cell and cell-tissue interactions. It is involved in the development and maintenance of tissues during embryonic development, and it plays a key role in the regulation of tissues during wound healing and tissue repair.

FGF-7 has also been shown to be involved in the development and progression of a variety of diseases, including cancer, neurodegenerative diseases, and developmental disorders. It is therefore a promising drug target for the development of new treatments for these diseases.

One of the key challenges in studying FGF-7 is its complex structure and function. FGF-7 is a large protein that contains multiple domains, including an extracellular domain, a transmembrane domain, and an intracellular domain. The extracellular domain is involved in interactions with the cell surface, while the transmembrane domain is involved in the regulation of cell-cell and cell-tissue interactions. The intracellular domain is involved in the regulation of gene expression.

Recent studies have identified several potential drug targets for FGF-7. One of the most promising targets is the protein peptidase (SPOP), which is a transmembrane protein that is involved in the regulation of cell-cell interactions. SPOP and FGF-7 The interaction can regulate FGF-7 signaling, thereby affecting cell proliferation and differentiation. In addition, some studies have also shown that the loss of SPOP can lead to dysregulation of FGF-7 signaling, leading to tumorigenesis. Therefore, SPOP can be an effective FGF-7 inhibitor.

Another potential FGF-7 drug target is the protein type A (TGFF3), which is a transcription factor that is involved in the regulation of gene expression. The interaction between TGFF3 and FGF-7 can regulate FGF-7 signaling. Thereby affecting cell proliferation and differentiation. In addition, TGFF3 also participates together with FGF-7

Protein Name: Fibroblast Growth Factor 7

Functions: Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation

The "FGF7 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FGF7 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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