Target Name: FGF13
NCBI ID: G2258
Review Report on FGF13 Target / Biomarker Content of Review Report on FGF13 Target / Biomarker
FGF13
Other Name(s): fibroblast growth factor homologous factor 2 | DEE90 | FGF-13 | FHF-2 | Fibroblast growth factor 13 (isoform 4) | Fibroblast growth factor 13, transcript variant 1 | FGF13 variant 2 | Fibroblast growth factor 13 | Fibroblast growth factor 13 (isoform 1) | OTTHUMP00000024143 | FGF13 variant 1 | Fibroblast growth factor 13, transcript variant 4 | OTTHUMP00000024144 | fibroblast growth factor 13 | LINC00889 | FHF2 | FGF2 | FGF13 variant 4 | Fibroblast growth factor 13, transcript variant 2 | Fibroblast growth factor homologous factor 2 | OTTHUMP00000024145 | FGF13_HUMAN | Fibroblast growth factor 13 (isoform 2)

FGF13: Regulating Cell Proliferation and Tissue Repair

Fibroblast growth factor homologous factor 2 (FGF13) is a protein that plays a crucial role in cellular growth and development. It is a member of the fibroblast growth factor family, which is a group of proteins that are involved in the regulation of cell growth, differentiation, and survival. FGF13 is a key regulator of cell proliferation and has been implicated in a number of diseases, including cancer, neurodegenerative diseases, and developmental disorders.

FGF13 is a transmembrane protein that is expressed in a variety of tissues, including epithelial, muscle, and nervous system cells. It is a potent stimulator of cell proliferation, and has been shown to promote the growth and survival of a wide range of cell types. FGF13 signaling is highly dependent on its interactions with other proteins, including the transcription factor, p300.

One of the key functions of FGF13 is its ability to induce the production of extracellular matrix (ECM) components, such as collagen and glycosaminoglycans. These components are important for maintaining tissue structure and providing mechanical support, and are critical for the development and maintenance of tissues. FGF13 has been shown to play a key role in the regulation of ECM homeostasis, and is involved in a wide range of physiological processes, including embryonic development, tissue repair, and cancer progression.

In addition to its role in cell proliferation and ECM regulation, FGF13 is also involved in a number of signaling pathways that are important for cellular function. One of the most well-studied functions of FGF13 is its role in the regulation of cell adhesion. FGF13 has been shown to play a key role in the formation of tight junctions, which are a type of cell-cell adhesion structure that helps to maintain the integrity of tissues and is critical for the development and maintenance of tissues.

FGF13 is also involved in the regulation of cell migration, and has been shown to play a key role in the development of migrating tissues, such as the placenta and the liver. FGF13 has been shown to promote the migration of a wide range of cell types, including neural cells, and is involved in the regulation of the migratory properties of these cells.

In addition to its role in cell proliferation, migration and adhesion, FGF13 is also involved in a number of other signaling pathways that are important for cellular function. One of the most well-studied functions of FGF13 is its role in the regulation of cell signaling pathways that are involved in cell growth, differentiation, and survival. FGF13 has been shown to play a key role in the regulation of the PI3K/Akt signaling pathway, and is involved in the regulation of a wide range of cellular processes, including cell signaling, cell survival, and cell proliferation.

FGF13 is also involved in the regulation of tissue repair and regeneration. FGF13 has been shown to play a key role in the regulation of cell proliferation and regeneration in a variety of tissues, including the skin, heart, and liver. FGF13 has been shown to promote the growth and survival of stem cells, and is involved in the regulation of the stem cell niche.

In addition to its role in tissue repair and regeneration, FGF13 is also involved in the regulation of cancer progression. FGF13 has been shown to play a key role in the regulation of cancer cell proliferation and metastasis, and is involved in the development of a wide range of cancer types. FGF13 has been shown to promote the growth and survival of a wide range of cancer cells, including breast, lung, and ovarian cancers.

Overall, FGF13 is a highly inter

Protein Name: Fibroblast Growth Factor 13

Functions: Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules (By similarity). Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching (By similarity). Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus (By similarity). Regulates voltage-gated sodium channels transport and function (PubMed:15282281, PubMed:33245860). May also play a role in MAPK signaling (By similarity). Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons (By similarity)

The "FGF13 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FGF13 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

FGF13-AS1 | FGF14 | FGF14-AS1 | FGF14-AS2 | FGF14-IT1 | FGF16 | FGF17 | FGF18 | FGF19 | FGF2 | FGF20 | FGF21 | FGF22 | FGF23 | FGF3 | FGF4 | FGF5 | FGF6 | FGF7 | FGF7P3 | FGF7P5 | FGF7P6 | FGF8 | FGF9 | FGFBP1 | FGFBP2 | FGFBP3 | FGFR1 | FGFR1OP2 | FGFR2 | FGFR3 | FGFR3P1 | FGFR4 | FGFRL1 | FGG | FGGY | FGL1 | FGL2 | FGR | FH | FHAD1 | FHDC1 | FHF Complex | FHIP1A | FHIP1B | FHIP2A | FHIP2B | FHIT | FHL1 | FHL2 | FHL3 | FHL5 | FHOD1 | FHOD3 | FIBCD1 | FIBIN | FIBP | Fibrinogen | Fibroblast growth factor (FGF) | Fibroblast Growth Factor Receptor (FGFR) | Fibronectin Type III Domain | FICD | FIG4 | FIGLA | FIGN | FIGNL1 | FIGNL2 | FILIP1 | FILIP1L | FILNC1 | FIP1L1 | FIRRE | FIS1 | FITM1 | FITM2 | Five friends of methylated CHTOP complex | FIZ1 | FJX1 | FKBP10 | FKBP11 | FKBP14 | FKBP15 | FKBP1A | FKBP1A-SDCBP2 | FKBP1B | FKBP1C | FKBP2 | FKBP3 | FKBP4 | FKBP5 | FKBP6 | FKBP7 | FKBP8 | FKBP9 | FKBP9P1 | FKBPL | FKRP | FKSG29 | FKTN | FLACC1