DPH7: A Potential Drug Target and Biomarker for Various Diseases

Target Name: DPH7

NCBI ID: G92715

DPH7

DPH7: A Potential Drug Target and Biomarker for Various Diseases

DPH7 (Dipeptidyl-peptidase 7) is a protein that is expressed in various cell types of the human body, including the brain. It is a member of the serine proteases family 7, which includes other enzymes that are involved in the degradation of peptides and proteins. The function of DPH7 is not well understood, but it is involved in the regulation of various cellular processes, including cell signaling, neurotransmitter clearance, and inflammation.

DPH7 has also been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. In this article, we will explore the biology and clinical potential of DPH7 as a drug target and biomarker.

Biology of DPH7

DPH7 is a 21-kDa protein that is expressed in the brain and other tissues of the body. It is localized to the endoplasmic reticulum (ER) and the trans-endosomal system (TES), which are systems for the transport of proteins between the cytosol and the endoplasmic reticulum. DPH7 is involved in the regulation of protein degradation and has been shown to play a role in the degradation of several proteins, including the neurotransmitter serotonin (5-HT).

In addition to its role in protein degradation, DPH7 is also involved in the regulation of cellular signaling pathways. It has been shown to be involved in the regulation of several intracellular signaling pathways, including the signaling pathway involving neurotransmitter release. DPH7 has also been shown to play a role in the regulation of cell growth and differentiation, as well as in the regulation of cell survival.

Clinical Potential of DPH7 as a Drug Target

DPH7 has been identified as a potential drug target for the treatment of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. One of the reasons for its potential as a drug target is its involvement in several key signaling pathways that are involved in the development and progression of these diseases.

For example, DPH7 has been shown to be involved in the regulation of the angiogenesis process, which is the process by which new blood vessels are formed in the body. DPH7 has been shown to play a role in the regulation of angiogenesis by promoting the degradation of the vasculogenic factor, which is a protein that promotes blood vessel formation.

In addition to its role in angiogenesis, DPH7 has also been shown to be involved in the regulation of several other signaling pathways that are involved in the development and progression of cancer, neurodegenerative diseases, and autoimmune disorders. For example, DPH7 has been shown to play a role in the regulation of the PI3K/Akt signaling pathway, which is involved in the regulation of cell survival and proliferation.

DPH7 has also been shown to be involved in the regulation of the TGF-β signaling pathway, which is involved in the regulation of cell growth and differentiation. In addition, DPH7 has been shown to play a role in the regulation of the NF-kappa-B signaling pathway, which is involved in the regulation of inflammation and immune responses.

DPH7 has also been shown to be involved in the regulation of several biomarkers that are used to diagnose and monitor various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, DPH7 has been shown to be involved in the regulation of the level of the protein S100, which is a biomarker for cancer.

In conclusion, DPH7 is a protein that is involved in several key signaling pathways that are involved in the development and progression of various diseases. As a result, DPH7 has

Protein Name: Diphthamide Biosynthesis 7

Functions: Catalyzes the demethylation of diphthine methyl ester to form diphthine, an intermediate diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) which can be ADP-ribosylated by diphtheria toxin and by Pseudomonas exotoxin A (Eta)

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•   expression level;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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