DPY19L3: A Potential Drug Target for Various Diseases (G147991)

Target Name: DPY19L3

NCBI ID: G147991

DPY19L3

DPY19L3: A Potential Drug Target for Various Diseases

DPY19L3, also known as Probable C-mannosyltransferase DPY19L3, is a protein that is expressed in various tissues and cells in the human body. It is a member of the C-mannosyltransferase family, which is a group of enzymes that transfer a manganese ion to the 2-carboxylic acid group of a client protein, allowing the client protein to interact with other proteins and form covalent bonds.

DPY19L3 is primarily localized to the endoplasmic reticulum (ER), where it is involved in the transport of various proteins, including the zinc finger protein FZD10. FZD10 is a non-coding RNA molecule that is known to play a role in regulating gene expression and has been implicated in a variety of cellular processes, including cell survival, cell proliferation, and neurodegeneration.

In addition to its role in protein transport,DPY19L3 is also involved in the regulation of gene expression. It has been shown to play a role in the negative regulation of FZD10 gene expression by binding to its mRNA and preventing its translation into protein. This interaction betweenDPY19L3 and FZD10 is important for understanding the regulation of FZD10 activity and its potential as a drug target.

DPY19L3 has also been shown to play a role in the regulation of cellular signaling pathways. It has been shown to interact with the protein kinase kinase A1 (PKA), which is involved in the regulation of cell growth, differentiation, and survival. This interaction betweenDPY19L3 and PKA suggests that it may be a potential drug target for the treatment of various diseases associated with PKA activity.

DPY19L3 is also involved in the regulation of cellular transport processes. It has been shown to play a role in the transport of various proteins, including the protein involved in the development and maintenance of blood vessels, called PDGF1. This interaction between DPY19L3 and PDGF1 suggests that it may be a potential drug target for the treatment of cardiovascular diseases associated with PDGF1 activity.

In conclusion, DPY19L3 is a protein that is involved in a variety of cellular processes and functions. Its involvement in the regulation of protein transport, gene expression, and cellular signaling pathways suggests that it may be a potential drug target for the treatment of various diseases . Further research is needed to fully understand its role and potential as a drug target.

Protein Name: Dpy-19 Like C-mannosyltransferase 3

Functions: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins

The "DPY19L3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DPY19L3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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