Target Name: SRCAP
NCBI ID: G10847
Review Report on SRCAP Target / Biomarker Content of Review Report on SRCAP Target / Biomarker
SRCAP
Other Name(s): SRCAP_HUMAN | Snf2-related CBP activator protein | Snf2-related CBP activator | Domino homolog 2 | EAF1 | KIAA0309 | Snf2 related CREBBP activator protein | DOMO1 | SWR1 | FLHS | DEHMBA | domino homolog 2 | Swi2/Snf2-related ATPase homolog, domino homolog 1 | Helicase SRCAP

SRCAP Plays A Role in Neurological and Psychiatric Disorders

SRCAP (SRCAP_HUMAN) is a protein that is expressed in various tissues of the human body. It is a member of the Src family of proteins, which are known for their role in cell signaling and cytoskeletal organization. SRCAP is primarily expressed in the brain and nervous system, and has been shown to play a role in the development and progression of various neurological disorders, including Alzheimer's disease and Parkinson's disease.

SRCAP is composed of 21 amino acid residues and has a calculated molecular weight of 19.3 kDa. It is expressed in a variety of tissues, including the brain, heart, and liver. It is primarily expressed in the brain, and is found in high concentrations in the prefrontal cortical cortex, a region of the brain that is involved in various cognitive functions.

SRCAP has been shown to play a role in the development and progression of various neurological disorders, including Alzheimer's disease and Parkinson's disease. Studies have shown that SRCAP is highly expressed in the brains of individuals with Alzheimer's disease, and that it is involved in the development of neurofibrillary tangles and beta-amyloid plaques, which are hallmark hallmarks of the disease. Similarly, SRCAP has been shown to be involved in the development and progression of Parkinson's disease, a disorder that is characterized by the loss of motor and cognitive abilities.

SRCAP has also been shown to play a role in the regulation of cellular signaling. It has been shown to interact with a variety of intracellular signaling pathways, including the tyrosine kinase pathway, the PI3K/Akt pathway, and the TGF-beta pathway. SRCAP has been shown to play a negative role in the regulation of this pathway, by inhibiting the activity of the protein p21.

SRCAP has also been shown to play a role in the regulation of the cytoskeleton. It has been shown to interact with the protein microtubule protein (MTP), which is involved in the regulation of cell division and the cytoskeleton. SRCAP has been shown to play a positive role in the regulation of this pathway, by increasing the stability of MTP on the microtubules.

SRCAP has also been shown to play a role in the regulation of inflammation. It has been shown to interact with the protein NF-kappa-B, which is involved in the regulation of inflammation and cellular signaling. SRCAP has been shown to play a negative role in the regulation of this pathway, by inhibiting the activity of the protein NF-kappa-B.

SRCAP has also been shown to play a role in the regulation of cell survival. It has been shown to interact with the protein Bcl-2, which is involved in the regulation of cell survival and apoptosis. SRCAP has been shown to play a positive role in the regulation of this pathway, by increasing the activity of the protein Bcl-2.

SRCAP has also been shown to play a role in the regulation of the cytoskeleton. It has been shown to interact with the protein Myosin, which is involved in the regulation of muscle contraction and the cytoskeleton. SRCAP has been shown to play a positive role in the regulation of this pathway, by increasing the activity of the protein Myosin.

SRCAP has also been shown to play a role in the regulation of the immune system. It has been shown to interact with the protein PDGF-R2, which is involved in the regulation of cell growth and differentiation, and the immune response. SRCAP has been shown to play a negative role in the regulation of this pathway, by inhibiting the activity of the protein PDGF-R2.

SRCAP has also been shown to play a role in the regulation of the cell cycle. It has been shown to interact with the protein

Protein Name: Snf2 Related CREBBP Activator Protein

Functions: Catalytic component of the SRCAP complex which mediates the ATP-dependent exchange of histone H2AZ/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling. Acts as a coactivator for CREB-mediated transcription, steroid receptor-mediated transcription, and Notch-mediated transcription

The "SRCAP Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SRCAP comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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SRCIN1 | SRD5A1 | SRD5A1P1 | SRD5A2 | SRD5A3 | SRD5A3-AS1 | SREBF1 | SREBF2 | SREBF2-AS1 | SREK1 | SREK1IP1 | SRF | SRFBP1 | SRGAP1 | SRGAP2 | SRGAP2B | SRGAP2C | SRGAP2D | SRGAP3 | SRGN | SRI | SRI-AS1 | SRL | SRM | SRMS | SRP14 | SRP14-DT | SRP19 | SRP54 | SRP54-AS1 | SRP68 | SRP72 | SRP9 | SRP9P1 | SRPK1 | SRPK2 | SRPK3 | SRPRA | SRPRB | SRPX | SRPX2 | SRR | SRRD | SRRM1 | SRRM1P1 | SRRM2 | SRRM2-AS1 | SRRM3 | SRRM4 | SRRM5 | SRRT | SRSF1 | SRSF10 | SRSF11 | SRSF12 | SRSF2 | SRSF3 | SRSF3P2 | SRSF4 | SRSF5 | SRSF6 | SRSF6P1 | SRSF7 | SRSF8 | SRSF9 | SRXN1 | SRY | SS18 | SS18L1 | SS18L2 | SSB | SSBP1 | SSBP2 | SSBP3 | SSBP3-AS1 | SSBP3P2 | SSBP4 | SSC4D | SSC5D | SSH1 | SSH2 | SSH3 | SSMEM1 | SSNA1 | SSPN | SSPOP | SSR1 | SSR1P2 | SSR2 | SSR3 | SSR4 | SSR4P1 | SSRP1 | SST | SSTR1 | SSTR2 | SSTR3 | SSTR4 | SSTR5 | SSTR5-AS1