SLC24A4 as A Potential Drug Target for Cancer and Neurodegenerative Diseases

Target Name: SLC24A4

NCBI ID: G123041

SLC24A4

SLC24A4 as A Potential Drug Target for Cancer and Neurodegenerative Diseases

SLC24A4 (NCKX4_HUMAN) is a protein that is expressed in various tissues of the human body. It is a member of the SLC24 family, which includes several related proteins that are involved in the transport of various molecules across cell membranes. One of the unique features of SLC24A4 is its ability to interact with the protein NCKX4, which is also known as NF-kappa-B signaling protein.

The NCKX4 protein is a non-coding RNA molecule that plays a role in the regulation of various cellular processes, including inflammation, stress, and survival. It is a potent transcriptional regulator that can activate or repress the expression of various genes in response to different stimuli. NCKX4 has been shown to play a role in the development and progression of various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

SLC24A4 has been identified as a potential drug target or biomarker for several reasons. Firstly, it is a conserved protein that is highly conserved across various species, which suggests that it is a promising candidate for targeting diseases that affect multiple organisms. Secondly, it is located in the cell membrane, which makes it an attractive target for small molecules that can cross-talk with it. Lastly, its expression is known to be regulated by various signaling pathways, including NF-kappa-B signaling pathway, which makes it a potential target for drugs that can modulate this pathway.

SLC24A4 has been shown to play a role in several cellular processes, including cell adhesion, migration, and invasion. It is a critical protein for the regulation of cell-cell adhesion, which is essential for the maintenance of tissue structure and function. has been shown to be involved in the regulation of tight junction formation, which is a critical aspect of cell-cell adhesion.

SLC24A4 has also been shown to play a role in the regulation of cell migration and invasion. It is a critical protein for the regulation of cell migration, which is essential for the development and progression of cancer. SLC24A4 has been shown to be involved in the regulation of cell invasiveness, which is a critical aspect of cancer cell migration.

In addition to its role in cell adhesion and migration, SLC24A4 has also been shown to play a role in the regulation of cell survival. It is a critical protein for the regulation of cell survival, which is essential for the development and progression of cancer. SLC24A4 has been shown to be involved in the regulation of cell apoptosis, which is a critical aspect of cancer cell survival.

SLC24A4 has also been shown to play a role in the regulation of inflammation. It is a critical protein for the regulation of inflammation, which is essential for the development and progression of various diseases, including cancer. SLC24A4 has been shown to be involved in the Regulation of inflammation-related signaling pathways, including NF-kappa-B signaling pathway.

In conclusion, SLC24A4 is a protein that has been identified as a potential drug target or biomarker for several reasons. Its conserved nature and its location in the cell membrane make it an attractive target for small molecules. Its expression is known to be regulated by various signaling pathways, including NF-kappa-B signaling pathway, which makes it a potential target for drugs that can modulate this pathway. Its role in cell adhesion, migration, and invasion, as well as its role in cell survival and inflammation, make it an attractive candidate for targeting diseases that affect multiple organisms. Further research is needed to determine the full extent of its potential as a drug target or biomarker.

Protein Name: Solute Carrier Family 24 Member 4

Functions: Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+) (PubMed:12379639, PubMed:26631410). Controls the rapid response termination and proper regulation of adaptation in olfactory sensory neurons (OSNs) which subsequently influences how odor information is encoded and perceived (By similarity). May play a role in calcium transport during amelogenesis (PubMed:23375655, PubMed:24621671)

The "SLC24A4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLC24A4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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