OR4D2: The Olfactory Receptor 4D2 as a Drug Target and Biomarker
OR4D2: The Olfactory Receptor 4D2 as a Drug Target and Biomarker
Smell is a crucial sense that helps humans identify and remember various objects, emotions, and environments. The olfactory system, which is responsible for processing and interpreting smells, is the primary sense organ responsible for this function. Olfactory receptors, which are present in the Nasal cavity, are the building blocks of the olfactory system. Olfactory receptor 4D2 (OR4D2), a subtype of olfactory receptor, is one of the most well-studied subtypes, and its functions in human perception and behavior have been extensively investigated.
OR4D2 is a transmembrane protein that is expressed in the epithelial cells of the nasal cavity. It is a member of the superfamily of G protein-coupled receptors (GPCRs), which are a subclass of protein tyrosine kinases that play a crucial role in cellular signaling . OR4D2 is characterized by its 4 transmembrane domains and a unique extracellular loop region that is rich in conserved amino acid sequences.
OR4D2 functions as a receptor for various stimuli, including sensory cues such as scents, fragrances, and chemicals. It is highly sensitive to agonists and has a wide range of affinity for different types of stimuli. OR4D2 has been shown to play a critical role in mediating the effects of various olfactory compounds, including odors, scents, and environmental chemicals.
OR4D2 is involved in several neural processes that are important for human perception and behavior. It is involved in the processing and classification of olfactory information, as well as in the modulation of behavioral responses to sensory stimuli. OR4D2 has been shown to be involved in the modulation of neural activity in the primary and secondary olfactory cortices, as well as in the basal ganglia.
OR4D2 has also been shown to be involved in several diseases and disorders, including cancer, neurodegenerative diseases, and psychiatric disorders. For example, studies have shown that decreased OR4D2 function is associated with several diseases, including Alzheimer's disease, Parkinson's disease, and schizophrenia.
Due to its involvement in several neural processes and its potential role in several diseases, OR4D2 has become an attractive drug target for researchers. Several studies have shown that inhibitors of OR4D2 can alleviate various neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and Schizophrenia.
In addition to its potential therapeutic applications, OR4D2 has also been shown to be a valuable biomarker for several diseases. For example, studies have shown that OR4D2 function is downregulated in various psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and schizophrenia. Additionally, decreased OR4D2 function has been shown to be associated with several cancer types, including breast, ovarian, and colorectal cancer.
In conclusion, Olfactory receptor 4D2 is a well-studied protein that is involved in several neural processes and plays a critical role in human perception and behavior. Its potential as a drug target and biomarker makes it an attractive target for researchers studying the mechanisms of various neurological and psychiatric disorders. Further research is needed to fully understand the functions of OR4D2 and its potential as a therapeutic agent.
Protein Name: Olfactory Receptor Family 4 Subfamily D Member 2
Functions: Odorant receptor
The "OR4D2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OR4D2 comprehensively, including but not limited to:
• general information;
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• protein biological mechanisms;
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• the target screening and validation;
• expression level;
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• drug resistance;
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• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
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