PABIR2: A Protein Target for Cancer and Neurodegenerative Diseases

Target Name: PABIR2

NCBI ID: G159090

PABIR2

PABIR2: A Protein Target for Cancer and Neurodegenerative Diseases

PABIR2 (RP11-308B5.5) is a protein that is expressed in various tissues of the body, including the brain, heart, liver, and kidneys. It is a member of the PABI (protein-protein interaction) family and is involved in the regulation of cellular processes such as cell adhesion, migration, and survival.

PABIR2 has been identified as a potential drug target due to its involvement in several disease processes, including cancer, neurodegenerative diseases, and autoimmune disorders. Its expression has also been associated with several diseases, including neurofibrillary tangles and senile plaques, which are hallmarks of Alzheimer's disease.

One of the key functions of PABIR2 is its role in the regulation of the protein PDGF-BB (Platelet-derived growth factor-beta), which is a potent regulator of cell proliferation and survival. PABIR2 has been shown to interact with PDGF-BB and regulate its activity, which may have implications for the regulation of cancer cell growth and survival.

In addition to its role in PDGF-BB signaling, PABIR2 is also involved in the regulation of several other signaling pathways, including TGF-beta, NF-kappa-B, and AP-1. Its expression has been shown to be regulated by factors such as cytokines, growth factors, and stress hormones, which may have implications for its role in the regulation of cellular processes that are relevant to a wide range of diseases.

PABIR2 has also been shown to be involved in the regulation of cellular transport processes, including the movement of proteins into and out of cells. This may be of interest in the context of diseases that are characterized by the accumulation of abnormal proteins in cells, such as neurodegenerative diseases.

In conclusion, PABIR2 is a protein that is involved in a wide range of cellular processes that are relevant to a variety of diseases. Its expression has been associated with the regulation of PDGF-BB signaling, and its role in the regulation of other signaling pathways may have implications for the regulation of cellular processes that are relevant to a wide range of diseases. As such, PABIR2 is a promising target for drug development in a variety of therapeutic areas, including cancer, neurodegenerative diseases, and autoimmune disorders.

Protein Name: PABIR Family Member 2

The "PABIR2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PABIR2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
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•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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