PABPC4L: A Promising Drug Target and Biomarker for Poly(A) Binding Protein-Cytoplasmic 4-like

Target Name: PABPC4L

NCBI ID: G132430

PABPC4L

PABPC4L: A Promising Drug Target and Biomarker for Poly(A) Binding Protein-Cytoplasmic 4-like

Poly(A) binding proteins (PABPs) are a family of transmembrane proteins that play a crucial role in various cellular processes, including DNA replication, transcription, and apoptosis. PABPs are involved in multiple cellular processes and are expressed in various tissues and cells. One of the PABPs, PABPC4L (poly(A) binding protein cytoplasmic 4 like), has been identified as a potential drug target and biomarker. In this article, we will discuss the biology of PABPC4L, its functions, potential drug targets, and potential use as a biomarker.

Biography of PABPC4L

PABPC4L is a 22 kDa protein that is expressed in various tissues, including brain, heart, and pancreas. It is a member of the PABP family and is characterized by its ability to bind to poly(A) bonds in the cytoplasm of various cell types. PABPC4L is involved in various cellular processes, including cell growth, apoptosis, and DNA replication.

PABPC4L is a protein that is composed of 121 amino acid residues. It has a calculated pI of 12.9 and a predicted localization in the cytoplasm of various cell types. PABPC4L is a cytoplasmic protein and is primarily localized to the cytoplasm of various cell types. It is a monomer and has no known ligands.

Function of PABPC4L

PABPC4L is involved in various cellular processes, including cell growth, apoptosis, and DNA replication. It is a key protein that is involved in the replication of DNA in the cytoplasm of various cell types. PABPC4L is a transcription factor that is involved in the regulation of gene expression. It is a cofactor of the transcription factor RNA polymerase II (RNA-P2) and is involved in the regulation of gene expression.

PABPC4L is also involved in apoptosis. It is a protein that is involved in the regulation of cell apoptosis, which is a natural process that helps remove damaged or dysfunctional cells from the body. PABPC4L is a key protein that is involved in the regulation of cell apoptosis and is involved in the protection of cells from apoptosis.

PABPC4L is also involved in DNA replication. It is a protein that is involved in the regulation of DNA replication and is involved in the replication of DNA in the cytoplasm of various cell types. PABPC4L is a key protein that is involved in the regulation of DNA replication and is involved in the protection of cells from DNA damage.

Potential Drug Targets

PABPC4L is a protein that is involved in various cellular processes, including cell growth, apoptosis, and DNA replication. As a result, it is a potential drug target. Several studies have identified potential drug candidates that can inhibit the activity of PABPC4L. These drugs can be used to treat various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

PABPC4L can be inhibited by small molecules, such as inhibitors of RNA-P2, a transcription factor that is activated by PABPC4L. In addition, PABPC4L can be inhibited by antibodies that specifically target the protein. These antibodies can be used to treat various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

PABPC4L can also be inhibited by modifying the activity of PABPC4L. For example, genetic modification can be used to alter the activity of PABPC4L. This can be done by introducing mutations in the PABPC4L gene or by using techniques such as CRISPR/Cas9 to modify the activity of PABPC4L. These modifications can be used to treat various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.

Potential Use as a Biomarker

PABPC4L is also

Protein Name: Poly(A) Binding Protein Cytoplasmic 4 Like

Functions: May bind RNA

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