Target Name: PABPN1L
NCBI ID: G390748
Review Report on PABPN1L Target / Biomarker Content of Review Report on PABPN1L Target / Biomarker
PABPN1L
Other Name(s): PABPN1 like, cytoplasmic | Embryonic polyadenylate-binding protein 2 | PABPN1 like, cytoplasmic, transcript variant 1 | EPAB2_HUMAN | Embryonic poly(A)-binding protein type II | poly(A) binding protein nuclear 1 like, cytoplasmic | poly(A)-binding protein nuclear-like 1 | Embryonic polyadenylate-binding protein 2 (isoform 1) | embryonic poly(A)-binding protein type II | embryonic polyadenylate-binding protein 2 | PABPNL1 | Embryonic poly(A)-binding protein 2 | embryonic poly(A) binding protein 2 | ePABP2 | embryonic poly(A)-binding protein 2 | PABPN1L variant 1 | Poly(A)-binding protein nuclear-like 1 | ePABP-2

Discovering The Potential of PABPN1L as A Drug Target

PABPN1L (PABPN1-like protein 1 like), also known as cytoplasmic protein PABPN1L, is a protein that is expressed in various cell types of the human body, including blood cells, nerve cells, and epithelial cells. PABPN1L is a member of the PABPN1 gene family, which is characterized by the presence of a characteristic conserved domain known as PABPN1.

PABPN1L is a cytoplasmic protein that is involved in various cellular processes, including cell adhesion, migration, and signaling. Its function in these processes is crucial for the development and maintenance of tissues and organs, and it is thought to play a key role in the regulation of inflammation and fibrosis.

Despite its importance, PABPN1L has not yet been identified as a drug target or biomarker. This lack of recognition has led to a limited understanding of its role in human disease, as well as a lack of research on the potential uses of PABPN1L as a therapeutic agent.

In this article, we will explore the biology and function of PABPN1L, with a focus on its potential as a drug target and biomarker. We will discuss the current state of research on PABPN1L, and identify potential future directions for research in this field.

PABPN1L biology and function

PABPN1L is a cytoplasmic protein that is expressed in various cell types of the human body. It is characterized by the presence of a characteristic conserved domain known as PABPN1, which is responsible for its unique structure and function.

PABPN1L is involved in various cellular processes, including cell adhesion, migration, and signaling. Its function in these processes is crucial for the development and maintenance of tissues and organs, and it is thought to play a key role in the regulation of inflammation and fibrosis.

One of the most significant functions of PABPN1L is its role in cell adhesion. PABPN1L is involved in the formation of tight junctions, which are a type of cell-cell adhesion that helps to maintain tissue structure and prevent excessive fluid out of cells.

In addition to its role in cell adhesion, PABPN1L is also involved in the regulation of cell migration. This is important for the development and maintenance of tissues and organs, as well as for the regulation of inflammation and fibrosis.

PABPN1L is also involved in signaling, both intracellular and extracellular. It is a potent signaling molecule that can induce the production of pro-inflammatory cytokines, such as TNF-伪 and IL-1尾, as well as the production of anti-inflammatory cytokines, such as IL-10.

In addition to its role in signaling, PABPN1L is also involved in the regulation of cellular signaling pathways that are important for cell growth, apoptosis, and inflammation.

PABPN1L as a drug target

PABPN1L is an attractive drug target due to its involvement in various cellular processes that are important for human health and disease. Its role in cell adhesion, migration, and signaling make it a potential target for small molecules that can modulate these processes.

One of the most promising strategies for targeting PABPN1L is the use of small molecules that can modulate its activity. This can be achieved through a variety of methods, including inhibition of PABPN1L signaling pathways, modulation of its cytoskeleton, or inhibition of its expression.

In addition to the use of small molecules, another strategy for targeting PABPN1L is the use of antibodies that can specifically recognize and target its cytoplasmic domain. This can be

Protein Name: PABPN1 Like, Cytoplasmic

Functions: Binds the poly(A) tail of mRNA

The "PABPN1L Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PABPN1L comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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