Target Name: SPRR4
NCBI ID: G163778
Review Report on SPRR4 Target / Biomarker Content of Review Report on SPRR4 Target / Biomarker
SPRR4
Other Name(s): small proline rich protein 4 | Small proline rich protein 4 | Small proline-rich protein 4 | MGC138375 | SPRR4_HUMAN | MGC138377 | OTTHUMP00000014401

SPRR4: A Potential Drug Target and Biomarker

Sprouting angiogenesis regulator (SPRR) family 4 (SPRR4) is a gene that has been identified as a potential drug target in the field of neurodegenerative diseases. SPRR4 is a transmembrane protein that is expressed in various tissues, including the brain, and is involved in the regulation of angiogenesis, the process by which new blood vessels are formed.

SPRR4 is known to play a crucial role in the development and maintenance of the blood-brain barrier, which is a barrier that separates the brain from the surrounding blood vessels and helps to protect the brain from harmful substances and diseases. The blood-brain barrier is highly selective, and it allows only certain substances to enter the brain and is critical for the healthy function of the brain.

SPRR4 is also involved in the regulation of the blood-brain barrier in diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. These conditions are characterized by the progressive loss of brain cells and the formation of aggregates of toxic substances, which can cause a range of symptoms.

SPRR4 has also been shown to be involved in the regulation of the growth and differentiation of neural stem cells. Neural stem cells are a type of cell that have the ability to develop into any type of cell in the nervous system, and they play a crucial role in the development and maintenance of the nervous system.

SPRR4 has also been shown to play a role in the regulation of the immune response. The immune system is a critical part of the body's defense against infection and disease, and it is important for maintaining the health and function of the brain.

In conclusion, SPRR4 is a gene that has the potential to be a drug target for a variety of neurodegenerative diseases. Further research is needed to fully understand the role of SPRR4 in these diseases and to develop effective treatments.

Protein Name: Small Proline Rich Protein 4

Functions: Cross-linked envelope protein of keratinocytes. Involved in UV-induced cornification

The "SPRR4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SPRR4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

SPRTN | SPRY1 | SPRY2 | SPRY3 | SPRY4 | SPRY4-AS1 | SPRY4-IT1 | SPRYD3 | SPRYD4 | SPRYD7 | SPSB1 | SPSB2 | SPSB3 | SPSB4 | SPTA1 | SPTAN1 | SPTB | SPTBN1 | SPTBN2 | SPTBN4 | SPTBN5 | SPTLC1 | SPTLC1P1 | SPTLC2 | SPTLC3 | SPTSSA | SPTSSB | SPTY2D1 | SPX | SPZ1 | SQLE | SQOR | SQSTM1 | SRA1 | SRARP | SRBD1 | SRC | SRCAP | SRCIN1 | SRD5A1 | SRD5A1P1 | SRD5A2 | SRD5A3 | SRD5A3-AS1 | SREBF1 | SREBF2 | SREBF2-AS1 | SREK1 | SREK1IP1 | SRF | SRFBP1 | SRGAP1 | SRGAP2 | SRGAP2B | SRGAP2C | SRGAP2D | SRGAP3 | SRGN | SRI | SRI-AS1 | SRL | SRM | SRMS | SRP14 | SRP14-DT | SRP19 | SRP54 | SRP54-AS1 | SRP68 | SRP72 | SRP9 | SRP9P1 | SRPK1 | SRPK2 | SRPK3 | SRPRA | SRPRB | SRPX | SRPX2 | SRR | SRRD | SRRM1 | SRRM1P1 | SRRM2 | SRRM2-AS1 | SRRM3 | SRRM4 | SRRM5 | SRRT | SRSF1 | SRSF10 | SRSF11 | SRSF12 | SRSF2 | SRSF3 | SRSF3P2 | SRSF4 | SRSF5 | SRSF6 | SRSF6P1