Target Name: SPSB3
NCBI ID: G90864
Review Report on SPSB3 Target / Biomarker Content of Review Report on SPSB3 Target / Biomarker
SPSB3
Other Name(s): splA/ryanodine receptor domain and SOCS box containing 3 | SplA/ryanodine receptor domain and SOCS box containing 3, transcript variant 1 | SPSB3 variant 1 | C16orf31 | SSB-3 | SPRY domain-containing SOCS box protein 3 | SSB3 | SPSB3_HUMAN | SPRY domain-containing SOCS box protein SSB-3

SPSB3 Plays A Crucial Role in Neural Development and Function

SPSB3, or splA/ryanodine receptor domain and SOCS box containing 3, is a protein that plays a critical role in the regulation of neural development and function. The splA gene, which encodes the splA protein, is located on chromosome 16 and has been implicated in the development and progression of various neurological disorders, including Alzheimer's disease and Parkinson's disease.

Theryanodine receptors, also known as TRK-1 or tyrosine kinase receptors, are a family of transmembrane proteins that play a key role in intracellular signaling. These receptors are involved in a wide range of physiological processes, including neurotransmitter signaling, cell survival, and cell migration.

The SPSB3 protein is a key component of the TRK-1 receptor, which is a protein that has been implicated in the development and progression of various neurological disorders, including Alzheimer's disease and Parkinson's disease. The SPSB3 protein is located in the TRK-1 receptor and is thought to play a critical role in the regulation of neurotransmitter signaling and intracellular signaling.

The SOCS box, which stands for short linear consensus sequence, is a conserved region of DNA that is located in the N-terminus of many proteins. The SOCS box is thought to play a critical role in the regulation of protein-protein interactions and in the regulation of cellular processes such as cell adhesion, migration, and survival.

SPSB3 is a 21-kDa protein that is expressed in a variety of tissues and cells, including neurons, glial cells, and other neural cell types. It is localized to the endoplasmic reticulum and is thought to play a critical role in the regulation of intracellular signaling pathways.

SPSB3 has been shown to play a critical role in the regulation of neurotransmitter signaling and intracellular signaling pathways. It is thought to interact with the TRK-1 receptor and the SOCS box, and is involved in the regulation of neurotransmitter signaling, including the regulation of dopamine and serotonin signaling.

SPSB3 is also involved in the regulation of cell adhesion and migration. It has been shown to play a critical role in the regulation of cell-cell adhesion and in the regulation of cell migration.

SPSB3 is also involved in the regulation of cellular processes such as cell survival and cytoskeletal organization. It has been shown to play a critical role in the regulation of cell survival and in the regulation of cytoskeletal organization.

In conclusion, SPSB3 is a protein that plays a critical role in the regulation of neural development and function. It is localized to the endoplasmic reticulum and is thought to play a critical role in the regulation of intracellular signaling pathways, including the regulation of neurotransmitter signaling, cell adhesion and migration, and cellular processes such as cell survival and cytoskeletal organization.

SPSB3 may be a drug target or biomarker for the treatment of various neurological disorders, including Alzheimer's disease and Parkinson's disease. Further research is needed to fully understand the role of SPSB3 in neural development and function, and to develop effective treatments for these disorders.

Protein Name: SplA/ryanodine Receptor Domain And SOCS Box Containing 3

Functions: May be a substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins

The "SPSB3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SPSB3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

SPSB4 | SPTA1 | SPTAN1 | SPTB | SPTBN1 | SPTBN2 | SPTBN4 | SPTBN5 | SPTLC1 | SPTLC1P1 | SPTLC2 | SPTLC3 | SPTSSA | SPTSSB | SPTY2D1 | SPX | SPZ1 | SQLE | SQOR | SQSTM1 | SRA1 | SRARP | SRBD1 | SRC | SRCAP | SRCIN1 | SRD5A1 | SRD5A1P1 | SRD5A2 | SRD5A3 | SRD5A3-AS1 | SREBF1 | SREBF2 | SREBF2-AS1 | SREK1 | SREK1IP1 | SRF | SRFBP1 | SRGAP1 | SRGAP2 | SRGAP2B | SRGAP2C | SRGAP2D | SRGAP3 | SRGN | SRI | SRI-AS1 | SRL | SRM | SRMS | SRP14 | SRP14-DT | SRP19 | SRP54 | SRP54-AS1 | SRP68 | SRP72 | SRP9 | SRP9P1 | SRPK1 | SRPK2 | SRPK3 | SRPRA | SRPRB | SRPX | SRPX2 | SRR | SRRD | SRRM1 | SRRM1P1 | SRRM2 | SRRM2-AS1 | SRRM3 | SRRM4 | SRRM5 | SRRT | SRSF1 | SRSF10 | SRSF11 | SRSF12 | SRSF2 | SRSF3 | SRSF3P2 | SRSF4 | SRSF5 | SRSF6 | SRSF6P1 | SRSF7 | SRSF8 | SRSF9 | SRXN1 | SRY | SS18 | SS18L1 | SS18L2 | SSB | SSBP1 | SSBP2 | SSBP3 | SSBP3-AS1